Evidence of Neutralizing Antibodies Indicating the Cure of PatientsInfected with COVID-19 Within one Month of Infection

Q4 Medicine

Anti-Infective Agents Pub Date : 2024-03-08 DOI:10.2174/0122113525284502240217161226

Yasir M. Abdulateef, Zainab N. Ayad, Haitham Noaman, Marwa F. Fadhel, Mahammad Z. Taha, Fatima M. Rafeeq, Ahmed Y. Salih

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引用次数: 0

Abstract

During COVID-19 pandemic a major conflict facing the clinician where to prove cure of the patients. The idea of confirming curability is based on clinical evaluation of the symptoms, laboratory investigations, and specific IgM, IgG anti-SARS-CoV2 antibodies. All patients had presented with clinical features of COVID-19 positive PCR attended private clinic doctors consultant in internal medicine and infectious diseases, they did investigations in Lagash land private medical laboratory in Baghdad investigated and screened for COVID-19 by S. ferritin, D-dimer, Complete blood picture and LDH. All were reevaluated in the first month of infection by clinical examination, retesting, and screening for COVID-19 IgM IgG later to prove cure or evidence of viral infection in PCR negative cases. All patients are of different ages with maximum years affected from adulthood till the age of one hundred years. Male were 170(54.3%) patients and females were 143 (45.7%) total 313 patients (100%). Most are moderate socioeconomic status, with a significant number having comorbidities. SARS COVID-19 IgM, IgG levels can be used to confirm a cure of the infection

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有证据表明，感染 COVID-19 的患者在感染后一个月内可治愈中和抗体

在 COVID-19 大流行期间，临床医生面临的一个主要矛盾是如何证明患者已经治愈。确认治愈的想法是基于临床症状评估、实验室检查和特异性 IgM、IgG 抗 SARS-CoV2 抗体。所有患者都曾出现过 COVID-19 阳性 PCR 的临床特征，都曾就诊于私人诊所的内科和传染病顾问医生，他们在巴格达的拉加什地私人医疗实验室进行了调查，并通过铁蛋白、D-二聚体、全血象和低密度脂蛋白胆固醇（LDH）对 COVID-19 进行了筛查。所有患者都在感染后的第一个月通过临床检查、复检和随后的 COVID-19 IgM IgG 筛查进行了评估，以证明 PCR 阴性病例已治愈或有病毒感染的证据。男性患者为 170 人（54.3%），女性患者为 143 人（45.7%），总计 313 人（100%）。大多数患者处于中等社会经济地位，相当多的患者患有并发症。

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来源期刊

Anti-Infective Agents Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

1.50

自引率

0.00%

发文量

期刊介绍： Anti-Infective Agents publishes original research articles, full-length/mini reviews, drug clinical trial studies and guest edited issues on all the latest and outstanding developments on the medicinal chemistry, biology, pharmacology and use of anti-infective and anti-parasitic agents. The scope of the journal covers all pre-clinical and clinical research on antimicrobials, antibacterials, antiviral, antifungal, and antiparasitic agents. Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health services.