Congenital Mullerian anomalies may lead to acute life threatening emergency in reproductive age group- An experience in a tertiary care centre in Eastern India

Abhijit Halder, Sabyasachi Sarkar, Mainak Nath, Manidip Pal
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Abstract

Congenital Mullerian anomalies are associated with higher incidence of reproductive failure and adverse obstetrical outcomes. The new ESHRE classification is a precise way to describe a genital anomaly in simple way. Many genital tract anomalies lead to devastating life-threatening conditions but under-reported and poorly explained. This study aims at finding out those anomalies which more frequently lead to specific diseases needing emergency intervention to save life of the patient. This longitudinal observational study evaluates the diagnosis and treatment of 12 patients with congenital Mullerian abnormalities which led to life threatening emergency with case discussion and pictorial documentation. Among 12 women with uterine anomalies 4 abortions, 7 delivered preterm, 1 term delivery occurred. Majority of complications associated with U3 types (58.3%). Other types with complications are U4 (25%) and U2 (16.7%). Presenting features at emergency varied like mimicking ectopic, labour complications, ruptured corpus, placenta previa and accreta as well as iatrogenic perforation. Presence of congenital uterine anomalies have adverse effect on obstetrical outcome. Majority of complications are associated with U2, U3 & U4. Probably U1 doesn’t interfere with ongoing pregnancy and U5 fails to continue pregnancy. This knowledge warrants the need for a larger case control study to extrapolate these findings to the general population and also to recommend the need for universal Prenatal Screening for uterine anomalies so as to improve the obstetrical outcome in patients with uterine anomalies.
先天性穆勒氏畸形可能导致育龄期人群出现危及生命的急症--印度东部一家三级医疗中心的经验之谈
先天性穆勒氏畸形与较高的生育失败率和不良产科预后有关。新的 ESHRE 分类法以简单的方式精确描述了生殖器异常。许多生殖道畸形都会导致危及生命的严重后果,但这些畸形却未得到充分报道和解释。本研究旨在找出那些更常导致需要紧急干预以挽救患者生命的特定疾病的异常情况。这项纵向观察研究通过病例讨论和图片记录,评估了 12 名先天性穆勒氏管畸形患者的诊断和治疗情况,这些畸形导致了危及生命的紧急情况。12 名子宫畸形妇女中有 4 人流产,7 人早产,1 人足月分娩。大多数并发症与 U3 类型有关(58.3%)。其他类型的并发症有 U4(25%)和 U2(16.7%)。急诊时的表现特征各不相同,如模仿宫外孕、分娩并发症、胎体破裂、前置胎盘、胎盘早剥以及先天性穿孔。先天性子宫畸形对产科结果有不利影响。大多数并发症与 U2、U3 和 U4 有关。可能 U1 不影响继续妊娠,而 U5 则无法继续妊娠。有鉴于此,有必要进行更大规模的病例对照研究,以便将这些发现推广到普通人群中,同时建议有必要普及子宫异常产前筛查,以改善子宫异常患者的产科预后。
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