The comparison of hot and cold executive functions in patients with bipolar II disorder, borderline personality disorder, and healthy individuals

Ayyub Sabbah, Shekoofeh Mottaghi, Parviz Ghaedi, Melika Ghalandari
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Abstract

Differential diagnosis of bipolar II disorder (BD-II) and borderline personality disorder (BPD) has always been challenging for clinicians due symptoms’ overlap. This study aimed to compare hot and cold executive functions (EFs) in BDII patients, BPD and healthy controls (HCs) in order to differentiate these two disorders. In the present study, 30 BDII and 30 BPD patients, undergoing the drug therapy with mood stabilizers, and 30 HC were examined using EFs evaluated tests. The data were then analyzed with the use of ANOVA and Tukey post hoc test. The BD-II Patients had significantly lower performance in all of the cold EFs than the HC. Also, BPD Patients had meaningfully lesser performance compared to HC in all cold EFs except the sustained attention. No significant difference was perceived between the two patient groups in the cold EFs. In BD-II patients, the risky decision-making as a hot EFs’ component was not significantly different from HC; nevertheless, its amount was significantly higher in BPD than the HC and BD-II patients. These findings underline the differences between two mentioned disorders based on the hot EFs, which may indicate further disorder in emotional information processing system among the BPD patients.
双相情感障碍 II 患者、边缘型人格障碍患者和健康人冷热执行功能的比较
由于双相情感障碍 II(BD-II)和边缘型人格障碍(BPD)的症状重叠,临床医生对这两种疾病的鉴别诊断一直面临挑战。本研究旨在比较双相情感障碍 II 患者、边缘型人格障碍患者和健康对照组(HCs)的冷热执行功能(EFs),以区分这两种障碍。 在本研究中,30 名正在接受情绪稳定剂药物治疗的 BDII 和 BPD 患者以及 30 名健康对照者接受了执行功能评估测试。然后使用方差分析和 Tukey 后验法对数据进行分析。 BD-II患者在所有冷EFs中的表现都明显低于HC。此外,除持续注意外,BPD 患者在所有冷EF方面的表现都明显低于HC。两组患者在冷EF方面没有明显差异。在 BD-II 患者中,作为热 EFs 组成部分的风险决策与 HC 没有显著差异;然而,BPD 患者的风险决策量显著高于 HC 和 BD-II 患者。 这些发现强调了上述两种疾病在热EFs方面的差异,这可能表明BPD患者的情绪信息处理系统进一步失调。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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