Could High-Density Lipoprotein (HDL) Alone be a Predictive Biomarker for Patients with Erectile Dysfunction?

Abstract

Objectives: The primary purpose of this study was to thoroughly examine high-density lipoprotein (HDL) levels as a predictor of erectile dysfunction (ED) in a cohort of 105 men aged 20 to 60 years. Since cardiovascular health and ED are connected, and dyslipidaemia can contribute, we aimed to determine whether HDL levels alone could be a reliable indicator of ED risk, independent of other factors. By analysing the interaction effects with variables such as BMI and smoking status, we sought to improve our understanding of lipid profiles in ED assessment and management. Methods: HDL levels in patients admitted to the urology department and diagnosed with ED between 2021 and 2022 were evaluated. Patients with diabetes mellitus, hypoandrogenemia, prostate surgery, or coronary heart disease were also excluded. Logistic regression analyses were performed to evaluate the association between low HDL levels (