Botulinum Toxin and Progressive Pneumoperitoneum in Loss of Domain Ventral Hernias: A Systematic Review

M. Giuffrida, Federico Biolchini, P. Capelli, F. Banchini, G. Perrone
{"title":"Botulinum Toxin and Progressive Pneumoperitoneum in Loss of Domain Ventral Hernias: A Systematic Review","authors":"M. Giuffrida, Federico Biolchini, P. Capelli, F. Banchini, G. Perrone","doi":"10.3389/jaws.2024.12650","DOIUrl":null,"url":null,"abstract":"Introduction: Preoperative progressive pneumoperitoneum (PPP) and botulinum toxin A (BTX) have been used together in the preoperative preparation of patients with loss of domain hernias. This study aims to evaluate the efficacy and safety of the combined use of PPP and BTX.Methods: A systematic electronic search was performed according to the PRISMA criteria. A literature search of scientific articles was conducted up to December 2023. Articles were chosen based on the reference to BTX and PPP in loss of domain ventral hernias with a defect width greater than 10 cm before surgery. The GRADE methodology and the modified Newcastle-Ottawa scale were used to assess the quality of the studies.Results: The research yielded seven articles, with 217 patients analysed in total. BTX was performed 29.5 ± 1.7 days before surgery and PPP was inflated 14.8 ± 5.8 days before surgery. PPP complications were reported in 25.6% of patients, The average reduction of the volume of hernia (VH)/volume of the abdominal cavity (VAC) ratio was 7.6% (range 0.9%–15%). Only 40 patients (18.4%) required a PCS or TAR to repair the loss of domain hernias. The SSI and SSO rates were 17.5% and 26.2%, respectively. No differences in SSI and SSO rates were found between the different repair techniques. The recurrence rate was 5.9% (13/217). Recurrence was significantly higher in patients who underwent IPOM repair than other techniques (p < 0.001).Conclusion: BTX and PPP may be useful tools for the management of loss of domain hernias presenting lower SSI and SSO. The combination of BTX and PPP reduces the use of more invasive repair techniques.","PeriodicalId":502716,"journal":{"name":"Journal of Abdominal Wall Surgery","volume":"48 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Abdominal Wall Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3389/jaws.2024.12650","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: Preoperative progressive pneumoperitoneum (PPP) and botulinum toxin A (BTX) have been used together in the preoperative preparation of patients with loss of domain hernias. This study aims to evaluate the efficacy and safety of the combined use of PPP and BTX.Methods: A systematic electronic search was performed according to the PRISMA criteria. A literature search of scientific articles was conducted up to December 2023. Articles were chosen based on the reference to BTX and PPP in loss of domain ventral hernias with a defect width greater than 10 cm before surgery. The GRADE methodology and the modified Newcastle-Ottawa scale were used to assess the quality of the studies.Results: The research yielded seven articles, with 217 patients analysed in total. BTX was performed 29.5 ± 1.7 days before surgery and PPP was inflated 14.8 ± 5.8 days before surgery. PPP complications were reported in 25.6% of patients, The average reduction of the volume of hernia (VH)/volume of the abdominal cavity (VAC) ratio was 7.6% (range 0.9%–15%). Only 40 patients (18.4%) required a PCS or TAR to repair the loss of domain hernias. The SSI and SSO rates were 17.5% and 26.2%, respectively. No differences in SSI and SSO rates were found between the different repair techniques. The recurrence rate was 5.9% (13/217). Recurrence was significantly higher in patients who underwent IPOM repair than other techniques (p < 0.001).Conclusion: BTX and PPP may be useful tools for the management of loss of domain hernias presenting lower SSI and SSO. The combination of BTX and PPP reduces the use of more invasive repair techniques.
肉毒杆菌毒素与失域腹股沟疝中的进行性腹腔积气:系统回顾
导言:术前渐进性腹腔积气(PPP)和肉毒杆菌毒素 A(BTX)已被用于域缺失疝患者的术前准备。本研究旨在评估联合使用 PPP 和 BTX 的有效性和安全性:方法:根据 PRISMA 标准进行了系统的电子检索。对截至 2023 年 12 月的科学文章进行了文献检索。选择文章的依据是在手术前对缺损宽度大于 10 厘米的腹股沟疝缺失进行 BTX 和 PPP 治疗的参考文献。采用 GRADE 方法和改良的纽卡斯尔-渥太华量表评估研究质量:研究共发表了 7 篇文章,分析了 217 名患者。BTX在术前29.5±1.7天进行,PPP在术前14.8±5.8天充气。据报告,25.6%的患者出现了 PPP 并发症,疝气体积(VH)/腹腔体积(VAC)比值平均减少了 7.6%(范围为 0.9%-15%)。只有 40 名患者(18.4%)需要进行 PCS 或 TAR 来修复疝域缺失。SSI和SSO率分别为17.5%和26.2%。不同修复技术的 SSI 和 SSO 发生率没有差异。复发率为 5.9%(13/217)。接受IPOM修复术的患者复发率明显高于其他技术(P < 0.001):结论:BTX 和 PPP 是治疗 SSI 和 SSO 较低的失疝的有效手段。BTX 和 PPP 的联合使用可减少创伤性更强的修复技术的使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信