Diffuse cerebral microhemorrhages in Wiskott-Aldrich syndrome – A rare radiological manifestation of a rare immunodeficiency disorder

Abstract

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency disorder with the characteristic triad of immunodeficiency, thrombocytopenia, and eczema. It results from a genetic mutation in the gene encoding WAS protein. We present a case of a 4-year-old male child who presented with two episodes of generalised tonic clonic seizures (GTCS) type convulsions. Magnetic resonance imaging (MRI) brain with contrast revealed diffuse cerebral microhemorrhages in supratentorial and infratentorial brain parenchyma which is a rare manifestation and not adequately documented in literature to the best of our knowledge.