Physical exercises as an effective adjuvant therapy of IBD in remission (review)

Abstract

Inflammatory bowel diseases (IBD) include Crohn’s disease and ulcerative colitis. IBDs are chronic diseases with a trajectory of remission and relapse. Drug therapy for IBD is not effective enough. There is a need for adjuvant therapy for IBD. The purpose of this review was to present the role of exercise and its impact on IBD. In this regard, a search is underway for additional tools to increase the frequency of achieving and maintaining remission. There is recent evidence that exercise induces a cascade of anti-inflammatory cytokines, specifically triggered by an exponential increase in muscle interleukin 6, and with regular exercise during remission may reduce basal levels of circulating inflammatory markers and potentially reduce chronic inflammation in IBD. Doctor’s recommendations for physical activity during remission can be effective as an additional component of anti-relapse treatment.