Influence of visceral manipulation on hormonal profile in women with polycystic ovarian syndrome: A randomized trial

Abstract

Background. Polycystic ovary syndrome (PCOS) is the most common endocrine condition in women of reproductive age and has been suggested as a risk factor for cardiometabolic disease. Depending on which diagnostic criteria are applied, approximately 10–15% of the women of reproductive age are affected by PCOS.Objective. To examine how viscera manipulation Influences hormonal profile in women with PCO. Design. A prospective randomized single-blind controlled trial. Setting. Outpatient clinics of Sadat General Hospital. Methods. Thirty patients of PCO females were recruited and randomized into two equal groups: the control group received a diet guidelines therapy in the form of the hypocaloric Mediterranean diet for 12 weeks, and the study group received the same control group interventions in addition to visceral manipulation (VM). biochemical analysis (FSH & LH) and BMI was the primary outcome. All variables were measured at the baseline and after 12 weeks of the intervention. Results. Statistical analysis was done by using paired’ test which showed significant improvement in both groups. Therefore, using mixed design MANOVA and multiple pairwise comparison tests (Post hoc tests) for the BMI and LH/FSH ratio post-treatment revealed that there were significant decreases in LH/FSH ratio (p =0.007) in favor to group B when compared with group A, with no significant differences in BMI between both groups (p = 0.443), showing that VM group (B) is more effective than group (A) on biochemical analysis (p < 0.05). Conclusion. Using visceral manipulation with a standard program of hypocaloric Mediterranean diet has more beneficial effects on hormonal profile in women with PCO.