Effect of laparoscopic mini gastric bypass versus laparoscopic single anastomosis sleeve ileal bypass on serum iron and calcium levels

A. Nawar, Mostafa Baumy, Ahmed Eid, Ayman T. Mohamed
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Abstract

Although bariatric surgery techniques are very effective in the treatment of obesity, they are usually associated with evident nutritional deficiencies. Such operations require ongoing medical care along with vitamin (Vit) and nutrition supplements. Is to determine and compare the effect of Laparoscopic mini gastric bypass (MGB) versus laparoscopic single anastomosis sleeve ileal bypass (SASI) on serum iron and calcium levels. The current prospective Randomized controlled study included 62 patients who were randomly allocated into one of two equal groups. Group A (n=31) underwent MGB while group B (n=31) underwent SASI. Follow-up was designed for 6 and 12 months in both groups for the serum iron profile, serum folate, Vit B12, Vit D, parathyroid hormone, and calcium level. There was a statistically significant decrease in Excess weight loss (EWL)% in both groups after 1, 6, and 12 months and a significant EWL % in group A more than group B (P=0.045*). There was a statistically significant drop in the Iron profile components’ levels in both groups after 1, 6, and 12 months in comparison with the corresponding baseline levels. There was a statistically significant decrease in the calcium level as well as Vit D3 within both groups at 1, 6, and 12 months follow-up with a significant increase in Parathyroid hormone in both groups at the same interval of follow-up. Both MGB and SASI are effective methods for the treatment of morbid obesity. However, adherent follow-up for the Iron profile, Vit B12, Vit D3, parathyroid hormone, and calcium levels are mandatory.
腹腔镜迷你胃旁路术与腹腔镜单吻合袖状回肠旁路术对血清铁和钙水平的影响
尽管减肥手术技术在治疗肥胖症方面非常有效,但通常会伴随着明显的营养缺乏。此类手术需要持续的医疗护理以及维生素(Vit)和营养补充剂。 本研究旨在确定并比较腹腔镜迷你胃旁路术(MGB)与腹腔镜单吻合袖式回肠旁路术(SASI)对血清铁和钙水平的影响。 本前瞻性随机对照研究包括 62 名患者,他们被随机分配到两个相同的组别中。A 组(31 人)接受 MGB,B 组(31 人)接受 SASI。对两组患者的血清铁概况、血清叶酸、维生素 B12、维生素 D、甲状旁腺激素和钙水平分别进行了 6 个月和 12 个月的随访。 在 1、6 和 12 个月后,两组的超重率(EWL)均有统计学意义上的明显下降,且 A 组的超重率明显高于 B 组(P=0.045*)。与相应的基线水平相比,两组在 1、6 和 12 个月后的铁概况成分水平均有统计学意义上的显著下降。在 1 个月、6 个月和 12 个月的随访中,两组的钙水平和维生素 D3 都出现了统计学意义上的显著下降,而甲状旁腺激素在相同的随访时间段内都出现了显著上升。 MGB 和 SASI 都是治疗病态肥胖的有效方法。但是,必须坚持随访铁概况、维生素 B12、维生素 D3、甲状旁腺激素和钙水平。
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