Anti coauglants induced intracranial hemorrhage managed with decompressive craniectomy: A case report of lesson learned

Sagun Ghimire, Shikher Shrestha, Dinuj Shrestha, Ananta maharjan, Bibek Jaiswal, Prabin chaudhary, Sharon Sherpa
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Abstract

Intracerebral hemorrhage (ICH)secondary to use of anti-coagulants is one of the fearsome complications. Hemorrhage within the intracranial space due to such anti-coagulants results in expansion of the intracranial bleeding despite the reversal of anti-coagulants. Hence timely surgical intervention can be lifesaving. An elderly female who was undergoing management for her deranged coagulation parameters was found to be in a state of features suggestive of stroke. Patient was on regular anti-coagulants medication for her cardiology issues. CT scan showed intracranial hemorrhage which underwent expansion in same day hence decompressive craniectomy was done. In further stay in the ICU patient GCS was fluctuating but symptomatic improvement was noted. Anti-coagulants adjustment was done from cardiologist and further there was no expansion of intracranial bleeding with within normal coagulation parameters. Anti-coagulants are rampantly used in several cases . Despite the several complications there is desperate need of such medications for the betterment of the patient condition. Pharmacological management is major modality in reversal of OAC induced ICH but in rare cases in the background of OACs induced ICH there occurs expansion of hemorrhage. Hence the need for neurosurgical intervention whether be it minimal invasive surgery or decompressive craniectomy . In the background of less prevalence of OACs induced ICH, there is absence of robust guiding treatment protocol. Furthermore there exist minimal reported cases which underwent surgical intervention and resulted good prognosis.
抗鸦片剂诱发的颅内出血通过减压开颅术得到了控制:一例经验教训报告
因使用抗凝剂而继发的脑出血(ICH)是可怕的并发症之一。使用抗凝血剂引起的颅内出血会导致颅内出血扩大,尽管抗凝血剂已被逆转。因此,及时的手术干预可以挽救生命。 一名老年女性患者因凝血参数紊乱而接受治疗,发现其特征提示中风。患者因心脏病定期服用抗凝药物。CT 扫描显示患者有颅内出血,并在当天进行了扩容,因此对患者进行了颅骨减压切除术。在重症监护室继续住院期间,患者的 GCS 出现波动,但症状有所改善。心脏科医生对抗凝剂进行了调整,颅内出血没有扩大,凝血指标正常。 抗凝剂在一些病例中被大量使用。尽管存在多种并发症,但为了改善患者的病情,仍迫切需要使用此类药物。药物治疗是逆转 OAC 引起的 ICH 的主要方式,但在极少数情况下,OAC 引起的 ICH 会导致出血扩大。因此,无论是微创手术还是减压开颅手术,都需要神经外科介入治疗。 在 OACs 引起的 ICH 发病率较低的背景下,缺乏强有力的指导性治疗方案。此外,接受手术干预并获得良好预后的病例报道极少。
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