Does Lake Louise questionnaire interpret high-altitude headache as acute mountain sickness? Experience in the western Himalayas.

IF 2.7 4区医学 Q3 IMMUNOLOGY

Indian Journal of Medical Research Pub Date : 2024-02-01 Epub Date: 2024-04-04 DOI:10.4103/ijmr.ijmr_2127_21

Abhilash Unnikrishnan, Atul Shekhar, Dharmendra Kumar, Raksha Jaipurkar, Gaurav Sikri, Krishan Singh, Rahul Manral

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Abstract

Background objectives: High-altitude headache (HAH) and headache in acute mountain sickness (AMS) are common among lowlanders ascending to the high altitude and are often confused with one another. A pilot study was undertaken to analyze HAH and AMS cases in Indian lowlanders ascending to Leh city (3500 m) in western Himalayas.

Methods: A total number of 1228 Indian lowlanders, who ascended (fresh and re-inductees) by air and acclimatized, participated in this pilot study. The intensity of headache was assessed by the Visual Analogue Score. The parameters of HAH as per the International Classification of Headache Disorders-3 and 2018 Revised Lake Louise Questionnaire (LLQ) were used to differentiate HAH and AMS.

Results: Out of 1228 cases, 78 (6.4%) cases had headache, of which 24 (1.95%) cases were HAH only, 40 (3.25%) cases AMS only and 14 (1.14%) cases were defined as both HAH and AMS. There was a significant difference in heart rate [F (2,51) = (4.756), P =0.01] between these groups. It also showed a difference in the correlation between the parameters within the groups. The Odd's Ratio of AMS in fresh and re-inductees was found to be 4.5 and for HAH it was 4.33.

Interpretation conclusions: The findings of this study suggest that LLQ has a tendency of overestimating AMS by including HAH cases. Furthermore differential parameters exhibit differences when AMS and HAH are considered separately. Re-inductees showed a lower incidence of HAH and AMS.

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路易斯湖调查问卷是否将高海拔头痛解释为急性高山病？喜马拉雅山西部的经验。

背景目标：高海拔头痛（HAH）和急性高山症头痛（AMS）是低地人前往高海拔地区的常见病，两者经常被混淆。我们开展了一项试验性研究，分析印度低地居民前往喜马拉雅山西部雷城（海拔 3500 米）的高海拔头痛和急性高山症病例：共有 1228 名印度低地人参加了这项试点研究，他们都是乘飞机登山（新登山者和再次登山者）并适应了当地气候。头痛的强度通过视觉模拟评分进行评估。根据《国际头痛疾病分类-3》和 2018 年修订的路易斯湖问卷（LLQ）得出的 HAH 参数用于区分 HAH 和 AMS：在1228例病例中，78例（6.4%）有头痛，其中24例（1.95%）仅为HAH，40例（3.25%）仅为AMS，14例（1.14%）同时被定义为HAH和AMS。这些组别之间的心率存在明显差异[F (2,51) = (4.756)，P=0.01]。这也显示了组内参数之间相关性的差异。研究发现，新入选者和重新入选者的 AMS 的奇数比为 4.5，HAH 为 4.33：这项研究的结果表明，LLQ 有可能因为包括了 HAH 病例而高估 AMS。此外，当分别考虑 AMS 和 HAH 时，差异参数也会出现差异。再次入选者的 HAH 和 AMS 发生率较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Medical Research 医学-免疫学

CiteScore

5.80

自引率

2.40%

发文量

191

审稿时长

3-8 weeks

期刊介绍： The Indian Journal of Medical Research (IJMR) [ISSN 0971-5916] is one of the oldest medical Journals not only in India, but probably in Asia, as it started in the year 1913. The Journal was started as a quarterly (4 issues/year) in 1913 and made bimonthly (6 issues/year) in 1958. It became monthly (12 issues/year) in the year 1964.