Computational insights into dynamics and conformational stability of N-acetylmannosamine kinase mutations

Journal of Biomolecular Structure and Dynamics Pub Date : 2024-03-19 DOI:10.1080/07391102.2024.2323702

Ashraf B. Abdel-Naim, Pawan Kumar, Mohammed A. Bazuhair, Waleed Y. Rizg, Hatoon A. Niyazi, Khalil Alkuwaity, Hanouf A. Niyazi, Saif A. Alharthy, Steve Harakeh, Shafiul Haque, Amresh Prakash, Vijay Kumar

引用次数: 0

Abstract

The activity of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) is essential for the biosynthesis of sialic acid, which is involved in cellular processes in health and diseases. GNE contains an N-termin...

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通过计算深入了解 N-乙酰甘露糖胺激酶突变的动力学和构象稳定性

UDP-GlcNAc 2-epimerase/ManNAc 激酶（GNE）的活性对于参与健康和疾病中细胞过程的硅酸的生物合成至关重要。GNE 含有一个 N-末端...

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of Biomolecular Structure and Dynamics

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