Interpretation: use of autoantibodies in children

Hayley King, Antonis Tofias, Abbie Greenhill, Aidan Grimes, Khuen Foong Ng
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Abstract

Judicious use of autoantibodies in paediatrics can be challenging. Autoimmune conditions can present with a wide range of signs and symptoms, many of which are non-specific. In combination with clinical features and laboratory findings, autoantibodies can facilitate diagnosis and in certain cases inform prognosis. Evidence for use of autoantibodies to guide and monitor treatment is limited. Caution is necessary when interpreting adult studies. We summarise the use of autoantibodies in paediatric practice with a guide on how they may be used.
解读:在儿童中使用自身抗体
在儿科合理使用自身抗体是一项挑战。自身免疫性疾病可表现出多种体征和症状,其中许多是非特异性的。结合临床特征和实验室检查结果,自身抗体有助于诊断,在某些情况下还能为预后提供信息。使用自身抗体指导和监测治疗的证据有限。在解释成人研究时必须谨慎。我们总结了自身抗体在儿科实践中的应用,并提供了如何使用这些抗体的指南。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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