APPLICATION OF ARTIFICIAL INTELLIGENCE IN THE DIAGNOSIS OF THYROID CANCER WITH ENHANCED COMPUTED TOMOGRAPHY

IF 0.8 4区 医学 Q4 BIOPHYSICS
NA HAN, JINRUI FAN, DONGWEI CHEN, YAPENG WANG
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Abstract

Thyroid Cancer (TC) is a common malignant tumor, head and neck in the incidence of malignant tumors in the seventh, ranked fourth in the incidence in women. There are several methods to diagnose and recognize TC, such as ultrasonic, computed tomography (CT) and other means. While, it is an important role for CT examination in the diagnosis of TC, because it has the characteristics of objectivity, repeatability, and multi-dimensional imaging, and can clearly understand the scope and spatial characteristics of the lesion. CT has unique advantages in showing lymph nodes and distant metastases, such as coarse-walled or thick-walled ring calcification. The early diagnosis of TC mainly relies on manual labor, which is very inefficient. With the continuous development of information science, the construction of TC diagnosis and recognition models based on artificial intelligence (AI) has gradually become a research hotspot. At present, research on AI-based thyroid screening models mainly focuses on four aspects: first, thyroid region segmentation and image denoising based on image-omics; second, the establishment of a high-precision TC risk prediction model based on multi-omics data; third, screening of biomarkers of TC for clinical diagnosis; fourth, establish the early screening model of TC based on AI. This paper reviews the research status of the AI-based thyroid screening model based on the above four aspects. In addition, this paper also summarizes the main challenges faced by the current AI -based TC recognition and detection model and it proposes a new research idea for the future TC early screening research based on enhanced CT.

人工智能在利用增强型计算机断层扫描诊断甲状腺癌中的应用
甲状腺癌(TC)是一种常见的恶性肿瘤,在头颈部恶性肿瘤发病率中占第七位,在女性发病率中占第四位。诊断和识别TC有多种方法,如超声波、计算机断层扫描(CT)等手段。而CT检查在TC的诊断中具有重要作用,因为它具有客观性、可重复性、多维成像等特点,可以清晰地了解病变的范围和空间特征。CT 在显示淋巴结和远处转移灶方面具有独特优势,如粗壁或厚壁环状钙化。TC的早期诊断主要依靠人工,效率非常低。随着信息科学的不断发展,基于人工智能(AI)的TC诊断和识别模型的构建逐渐成为研究热点。目前,基于人工智能的甲状腺筛查模型研究主要集中在四个方面:一是基于图像组学的甲状腺区域分割和图像去噪;二是建立基于多组学数据的高精度TC风险预测模型;三是筛选TC的生物标志物用于临床诊断;四是建立基于人工智能的TC早期筛查模型。本文从以上四个方面回顾了基于人工智能的甲状腺筛查模型的研究现状。此外,本文还总结了目前基于人工智能的TC识别与检测模型所面临的主要挑战,并对未来基于增强CT的TC早期筛查研究提出了新的研究思路。
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来源期刊
Journal of Mechanics in Medicine and Biology
Journal of Mechanics in Medicine and Biology 工程技术-工程:生物医学
CiteScore
1.20
自引率
12.50%
发文量
144
审稿时长
2.3 months
期刊介绍: This journal has as its objective the publication and dissemination of original research (even for "revolutionary concepts that contrast with existing theories" & "hypothesis") in all fields of engineering-mechanics that includes mechanisms, processes, bio-sensors and bio-devices in medicine, biology and healthcare. The journal publishes original papers in English which contribute to an understanding of biomedical engineering and science at a nano- to macro-scale or an improvement of the methods and techniques of medical, biological and clinical treatment by the application of advanced high technology. Journal''s Research Scopes/Topics Covered (but not limited to): Artificial Organs, Biomechanics of Organs. Biofluid Mechanics, Biorheology, Blood Flow Measurement Techniques, Microcirculation, Hemodynamics. Bioheat Transfer and Mass Transport, Nano Heat Transfer. Biomaterials. Biomechanics & Modeling of Cell and Molecular. Biomedical Instrumentation and BioSensors that implicate ''human mechanics'' in details. Biomedical Signal Processing Techniques that implicate ''human mechanics'' in details. Bio-Microelectromechanical Systems, Microfluidics. Bio-Nanotechnology and Clinical Application. Bird and Insect Aerodynamics. Cardiovascular/Cardiac mechanics. Cardiovascular Systems Physiology/Engineering. Cellular and Tissue Mechanics/Engineering. Computational Biomechanics/Physiological Modelling, Systems Physiology. Clinical Biomechanics. Hearing Mechanics. Human Movement and Animal Locomotion. Implant Design and Mechanics. Mathematical modeling. Mechanobiology of Diseases. Mechanics of Medical Robotics. Muscle/Neuromuscular/Musculoskeletal Mechanics and Engineering. Neural- & Neuro-Behavioral Engineering. Orthopedic Biomechanics. Reproductive and Urogynecological Mechanics. Respiratory System Engineering...
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