Enigma of Acantholytic and Clear Cell Changes in Oral Squamous Cell Carcinoma.

IF 3.2 Q2 PATHOLOGY

Head & Neck Pathology Pub Date : 2024-03-15 DOI:10.1007/s12105-024-01611-y

Ayushi Jain, Sharon John, Shalini Gupta

引用次数: 0

Abstract

Only limited cases have been reported about the clear cell variant of squamous cell carcinoma occurring in the oral cavity. The present study regards the case showing the histopathological features of both the clear cell and acantholytic variants of oral squamous cell carcinoma. A review of the literature has been done to understand the pathogenesis of those changes. Also, a hypothesis has been given that the clear cell changes could be the consequences of the cascades of the acantholytic process and not a separate entity. Therefore, more research is required to confirm this hypothesis and understand the prognosis of the lesion.

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口腔鳞状细胞癌中的棘细胞和透明细胞变化之谜。

关于发生在口腔的鳞状细胞癌透明细胞变异型的报道非常有限。本研究的病例显示了口腔鳞状细胞癌透明细胞变异和棘细胞变异的组织病理学特征。为了了解这些变化的发病机制，我们对文献进行了回顾。此外，还提出了一个假设，即透明细胞的变化可能是棘层溶解过程的级联结果，而不是一个独立的实体。因此，需要进行更多的研究来证实这一假设，并了解病变的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Head & Neck Pathology PATHOLOGY-

CiteScore

5.70

自引率

9.50%

发文量

期刊介绍： Head & Neck Pathology presents scholarly papers, reviews and symposia that cover the spectrum of human surgical pathology within the anatomic zones of the oral cavity, sinonasal tract, larynx, hypopharynx, salivary gland, ear and temporal bone, and neck. The journal publishes rapid developments in new diagnostic criteria, intraoperative consultation, immunohistochemical studies, molecular techniques, genetic analyses, diagnostic aids, experimental pathology, cytology, radiographic imaging, and application of uniform terminology to allow practitioners to continue to maintain and expand their knowledge in the subspecialty of head and neck pathology. Coverage of practical application to daily clinical practice is supported with proceedings and symposia from international societies and academies devoted to this field. Single-blind peer review The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.

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