Predictors of Preterm Neonatal Mortality in India and Pakistan: A Secondary Analysis of Data from PURPOSe Study.

IF 1.4 Q3 PEDIATRICS

Global Pediatric Health Pub Date : 2024-03-13 eCollection Date: 2024-01-01 DOI:10.1177/2333794X241236617

Shiyam Sunder Tikmani, Sarah Saleem, Afreen Sadia, Carla M Bann, Muhammad Hayat Bozdar, Jamal Raza, Sangappa M Dhaded, Shivaprasad S Goudar, Guruparasad Gowdar, Haleema Yasmin, Elizabeth M McClure, Robert L Goldenberg

{"title":"Predictors of Preterm Neonatal Mortality in India and Pakistan: A Secondary Analysis of Data from PURPOSe Study.","authors":"Shiyam Sunder Tikmani, Sarah Saleem, Afreen Sadia, Carla M Bann, Muhammad Hayat Bozdar, Jamal Raza, Sangappa M Dhaded, Shivaprasad S Goudar, Guruparasad Gowdar, Haleema Yasmin, Elizabeth M McClure, Robert L Goldenberg","doi":"10.1177/2333794X241236617","DOIUrl":null,"url":null,"abstract":"Objective. To create a prediction model for preterm neonatal mortality. Methods. A secondary analysis was conducted using data from a prospective cohort study, the Project to Understand and Research Preterm Pregnancy Outcome South Asia. The Cox proportional hazard model was used and adjusted hazard ratios (AHR) with 95% confidence intervals (95% CI) were reported. Results. Overall, 3446 preterm neonates were included. The mean age of preterm neonates was 0.65 (1.25) hours and 52% were female. The preterm neonatal mortality rate was 23.3%. The maternal factors predicting preterm neonatal death was any antepartum hemorrhage, AHR 1.99 (1.60-2.47), while neonatal predictors were preterm who received positive pressure ventilation AHR 1.30 (1.08-1.57), temperature <35.5°C AHR 1.18 (1.00-1.39), and congenital malformations AHR 3.31 (2.64-4.16). Conclusion. This study identified key maternal and neonatal predictors of preterm neonatal mortality, emphasizing the need for targeted interventions and collaborative public health efforts to address disparities and regional variations.","PeriodicalId":12576,"journal":{"name":"Global Pediatric Health","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10938607/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global Pediatric Health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/2333794X241236617","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}

引用次数: 0

Abstract

Objective. To create a prediction model for preterm neonatal mortality. Methods. A secondary analysis was conducted using data from a prospective cohort study, the Project to Understand and Research Preterm Pregnancy Outcome South Asia. The Cox proportional hazard model was used and adjusted hazard ratios (AHR) with 95% confidence intervals (95% CI) were reported. Results. Overall, 3446 preterm neonates were included. The mean age of preterm neonates was 0.65 (1.25) hours and 52% were female. The preterm neonatal mortality rate was 23.3%. The maternal factors predicting preterm neonatal death was any antepartum hemorrhage, AHR 1.99 (1.60-2.47), while neonatal predictors were preterm who received positive pressure ventilation AHR 1.30 (1.08-1.57), temperature <35.5°C AHR 1.18 (1.00-1.39), and congenital malformations AHR 3.31 (2.64-4.16). Conclusion. This study identified key maternal and neonatal predictors of preterm neonatal mortality, emphasizing the need for targeted interventions and collaborative public health efforts to address disparities and regional variations.

查看原文本刊更多论文

印度和巴基斯坦早产新生儿死亡率的预测因素：对 PURPOSe 研究数据的二次分析。

目的：建立早产新生儿死亡率预测模型。建立早产新生儿死亡率预测模型。方法。利用一项前瞻性队列研究--"南亚早产妊娠结果了解与研究项目 "的数据进行了二次分析。使用了 Cox 比例危险模型，并报告了调整后的危险比 (AHR) 和 95% 置信区间 (95% CI)。研究结果共纳入 3446 名早产新生儿。早产新生儿的平均年龄为 0.65 (1.25) 小时，52% 为女性。早产新生儿死亡率为 23.3%。预测早产新生儿死亡的母体因素是产前出血，AHR 1.99（1.60-2.47），而预测新生儿死亡的因素是接受正压通气的早产儿，AHR 1.30（1.08-1.57），体温结论。这项研究确定了早产新生儿死亡的主要孕产妇和新生儿预测因素，强调了有必要采取有针对性的干预措施和公共卫生合作努力，以解决差异和地区差异问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊