Electrospun PCL-Based Materials for Health-Care Applications: An Overview

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL

ACS Applied Energy Materials Pub Date : 2024-03-13 DOI:10.1002/mame.202300388

Teboho Clement Mokhena, Mandla Brian Chabalala, Sivuyisiwe Mapukata, Asanda Mtibe, Lerato Hlekelele, Zamani Cele, Mokgaotsa Jonas Mochane, Bulelwa Ntsendwana, Toitoi Amos Nhlapo, Teboho Patrick Mokoena, Mokae Fanuel Bambo, Kgabo Phillemon Matabola, Suprakas Sinha Ray, Emmanuel Rotimi Sadiku, Katekani Shingange

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Abstract

Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL-based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.

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用于保健应用的电纺 PCL 基材料：概述

聚己内酯（PCL）是一种耐用聚合物，在大量医疗保健应用中具有潜力。它的生物特性、可降解性、化学特性和机械特性可被进一步改良，以制造现代生物医学应用所需的产品。PCL 的电纺丝技术为设计类似人体组织的治疗材料提供了机会，可促进目标部位的再生。此外，还可以通过添加其他活性功能材料对所制成的材料进行改性，从而扩大其应用范围。本文阐述了在制备和改性 PCL 基材料用于医疗保健应用方面的最新进展。此外，还概述了其在现代生物医学应用中面临的挑战和未来趋势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.