Prevalence of abnormal left ventricular global longitudinal strain by speckle tracking echocardiography and its prognostic value in patients with COVID-19

IF 2.8 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Open Heart Pub Date : 2024-03-01 DOI:10.1136/openhrt-2023-002397

Shruti Hegde, Mina Shnoda, Yasser Alkhadra, Adhiraj Bhattacharya, Maria Nikolaeva, Michael Maysky

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引用次数: 0

Abstract

Importance Although cardiac injury is a known complication of COVID-19 infection, there is no established tool to predict cardiac involvement and in-hospital mortality in this patient population. Objective To assess if left ventricular global longitudinal strain (LV-GLS) can detect cardiac involvement and be used as a risk-stratifying parameter for hospitalised patients with COVID-19. Main outcomes and measures In-hospital mortality. Results We found a statistically significant association between LV-GLS and in-hospital mortality (adjusted OR (aOR)=1.09; 95% CI 1.0 to 1.19, p=0.050). Furthermore, right ventricular fractional area change was significantly associated with in-hospital mortality (aOR=1.04; 95% CI 1.0 to 1.08, p=0.043). Troponin level had no statistically significant association with in-hospital mortality (aOR=3.43; 95% CI 0.78 to 15.03, p=0.101). Conclusion and relevance LV-GLS can be a useful parameter for cardiovascular risk assessment in hospitalised patients with COVID-19 infection. Data are available upon reasonable request. All data relevant to the study are included in the article or uploaded as supplementary information.

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斑点追踪超声心动图显示 COVID-19 患者左心室整体纵向应变异常的发生率及其预后价值

重要性虽然已知心脏损伤是 COVID-19 感染的一种并发症，但目前还没有一种成熟的工具可以预测该患者的心脏受累情况和院内死亡率。目的评估左心室整体纵向应变（LV-GLS）能否检测心脏受累情况，并将其作为 COVID-19 住院患者的风险分级参数。主要结果和测量住院死亡率。结果我们发现 LV-GLS 与院内死亡率之间存在统计学意义上的显著关联（调整 OR (aOR)=1.09; 95% CI 1.0 至 1.19，p=0.050）。此外，右心室折返面积变化与院内死亡率显著相关（aOR=1.04；95% CI 1.0 至 1.08，p=0.043）。肌钙蛋白水平与院内死亡率无统计学意义（aOR=3.43；95% CI 0.78 至 15.03，p=0.101）。结论与意义 LV-GLS 可以作为 COVID-19 感染住院患者心血管风险评估的有用参数。如有合理要求，可提供相关数据。所有与研究相关的数据均包含在文章中或作为补充信息上传。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Heart CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

4.60

自引率

3.70%

发文量

145

审稿时长

20 weeks

期刊介绍： Open Heart is an online-only, open access cardiology journal that aims to be “open” in many ways: open access (free access for all readers), open peer review (unblinded peer review) and open data (data sharing is encouraged). The goal is to ensure maximum transparency and maximum impact on research progress and patient care. The journal is dedicated to publishing high quality, peer reviewed medical research in all disciplines and therapeutic areas of cardiovascular medicine. Research is published across all study phases and designs, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Opinionated discussions on controversial topics are welcomed. Open Heart aims to operate a fast submission and review process with continuous publication online, to ensure timely, up-to-date research is available worldwide. The journal adheres to a rigorous and transparent peer review process, and all articles go through a statistical assessment to ensure robustness of the analyses. Open Heart is an official journal of the British Cardiovascular Society.