Tissue Engineering Scaffolds Loaded With a Variety of Plant Extracts: Novel Model in Breast Cancer Therapy.

IF 1.8 Q3 ONCOLOGY
Breast Cancer : Basic and Clinical Research Pub Date : 2024-03-11 eCollection Date: 2024-01-01 DOI:10.1177/11782234241236358
Reyhaneh Azhari Rad, Yasaman Naghdi, Mobina Majidi Jamalabadi, Sima Masoumi, Leila Rezakhani, Morteza Alizadeh
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引用次数: 0

Abstract

Despite recent improvements in detecting and managing breast cancer (BC), it continues to be a major worldwide health concern that annually affects millions of people. Exploring the anti-BC potentials of natural compounds has received a lot of scientific attention due to their multi-target mode of action and good safety profiles because of these unmet needs. Drugs made from herbs are secure and have a lot fewer negative effects than those made from synthetic materials. Early stage patients benefit from breast-conserving surgery, but the risk of local recurrence remains, necessitating implanted scaffolds. These scaffolds provide residual cancer cell killing and tailored drug delivery. This review looks at plant extract-infused tissue engineering scaffolds, which provide a novel approach to treating BC. By offering patient individualized, safer treatments, these scaffolds could completely change how BC is treated.

含有多种植物提取物的组织工程支架:乳腺癌治疗的新模式
尽管近年来在检测和控制乳腺癌(BC)方面取得了一些进展,但乳腺癌仍然是全球关注的一个主要健康问题,每年影响着数百万人。由于天然化合物具有多靶点作用模式和良好的安全性,因此探索天然化合物抗乳腺癌的潜力受到了科学界的广泛关注。与人工合成材料相比,草药制成的药物安全可靠,负面影响也少得多。早期患者可从保乳手术中获益,但局部复发的风险依然存在,因此有必要植入支架。这些支架可以杀死残留的癌细胞,并提供量身定制的药物输送。本综述探讨了注入植物提取物的组织工程支架,它为治疗乳腺癌提供了一种新方法。通过为患者提供个体化、更安全的治疗,这些支架可以彻底改变BC的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.10
自引率
3.40%
发文量
22
审稿时长
8 weeks
期刊介绍: Breast Cancer: Basic and Clinical Research is an international, open access, peer-reviewed, journal which considers manuscripts on all areas of breast cancer research and treatment. We welcome original research, short notes, case studies and review articles related to breast cancer-related research. Specific areas of interest include, but are not limited to, breast cancer sub types, pathobiology, metastasis, genetics and epigenetics, mammary gland biology, breast cancer models, prevention, detection, therapy and clinical interventions, and epidemiology and population genetics.
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