Plasmablastic Lymphoma. A State-of-the-Art Review: Part 2-Focus on Therapy.

IF 2 4区医学 Q3 HEMATOLOGY

Mediterranean Journal of Hematology and Infectious Diseases Pub Date : 2024-03-01 eCollection Date: 2024-01-01 DOI:10.4084/MJHID.2024.015

Michele Bibas

引用次数: 0

Abstract

The objective of this two-part review is to present a current and comprehensive understanding of the diagnosis and management of plasmablastic lymphoma. The first part, which was published previously, focused on the study of epidemiology, etiology, clinicopathological characteristics, differential diagnosis, prognostic variables, and the impact of plasmablastic lymphoma on specific populations. This second part addresses the difficult topic of the treatment of plasmablastic lymphoma, specifically examining both the conventional, consolidated approach and the novel therapeutic strategy.

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浆细胞性淋巴瘤。最新进展回顾：第二部分--聚焦治疗。

本综述由两部分组成，旨在介绍目前对浆细胞性淋巴瘤诊断和管理的全面认识。第一部分已经发表，重点研究流行病学、病因学、临床病理特征、鉴别诊断、预后变量以及浆细胞性淋巴瘤对特定人群的影响。第二部分探讨了浆细胞性淋巴瘤的治疗这一难题，特别研究了传统的综合治疗方法和新型治疗策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mediterranean Journal of Hematology and Infectious Diseases Medicine-Hematology

CiteScore

4.20

自引率

6.20%

发文量

113

审稿时长

12 weeks

期刊介绍： Reciprocal interdependence between infectious and hematologic diseases (malignant and non-malignant) is well known. This relationship is particularly evident in Mediterranean countries. Parasitosis as Malaria, Leishmaniosis, B Hookworms, Teniasis, very common in the southeast Mediterranean area, infect about a billion people and manifest prevalently with anemia so that they are usually diagnosed mostly by experienced hematologist on blood or bone marrow smear. On the other hand, infections are also a significant problem in patients affected by hematological malignancies. The blood is the primary vector of HIV infection, which otherwise manifest with symptoms related to a reduction in T lymphocytes. In turn, infections can favor the insurgency of hematological malignancies. The causative relationship between Epstein-Barr virus infection, Helicobacter pylori, hepatitis C virus, HIV and lymphoproliferative diseases is well known.