Characterization of Secondary Neutron Spectra from Therapeutic Proton and Carbon Ion Beams Using PHITS Simulation

IF 0.4 4区 物理与天体物理 Q4 PHYSICS, MULTIDISCIPLINARY
Mohamed El-Asery, Zouhair Sadoune, Hassane El Bekkouri, El Mehdi Al Ibrahmi, Abdessamad Didi, El Mahjoub Chakir
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Abstract

Hadron therapy (HT) is a technique that uses accelerated ions, notably protons, and carbon ions, to destroy tumors. It has demonstrated high success rates in the treatment of certain cancers resistant to irradiation. In HT, the majority of the dose is delivered to the tumor volume by electromagnetic interactions with atomic electrons. However, it is important to note that the primary particles used in HT can induce nuclear reactions, generating undesirable secondary radiation, certainly neutrons. As a result, a significant portion of the patients’ body may be exposed to the secondary background radiation field. Thus, these unwanted secondary neutrons should be evaluated. The purpose of this research in first is to characterize the secondary neutron production (SNP) during the administration of Hadrons with energies 140 MeV proton, and 264 MeV/u carbon ions (\({}^{12}\)C) in a soft tissue phantom. Second, comparing the neutron spectrum for different angles for protons and carbon ions for carbon targets to experimental data. Our results show that the neutron spectra (thick target neutron yields TTNYs ) at energies less than \(\thickapprox\)20 MeV, using the INCL4.6/GEM models and JQMD/GEM across a wide range would be suitable for the Monte Carlo transport simulation.

Abstract Image

Abstract Image

利用 PHITS 仿真分析治疗性质子束和碳离子束产生的二次中子谱特性
摘要 哈德龙疗法(HT)是一种利用加速离子(主要是质子和碳离子)摧毁肿瘤的技术。它在治疗某些对照射有抵抗力的癌症方面取得了很高的成功率。在高温热疗中,大部分剂量是通过与原子电子的电磁相互作用传递到肿瘤部位的。但必须注意的是,高温热疗中使用的原生粒子会诱发核反应,产生不良的二次辐射,当然也包括中子。因此,患者身体的很大一部分可能会暴露在二次本底辐射场中。因此,应该对这些有害的二次中子进行评估。这项研究的目的首先是描述在软组织模型中施用能量为 140 MeV 质子和 264 MeV/u 碳离子(\({}^{12}\)C)的强子时产生的二次中子(SNP)。其次,将质子和碳离子在碳靶不同角度的中子谱与实验数据进行比较。我们的结果表明,使用INCL4.6/GEM模型和JQMD/GEM在很大范围内得到的能量小于\(thickapprox\)20 MeV的中子谱(厚靶中子产率TTNYs)将适合蒙特卡罗输运模拟。
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来源期刊
Moscow University Physics Bulletin
Moscow University Physics Bulletin PHYSICS, MULTIDISCIPLINARY-
CiteScore
0.70
自引率
0.00%
发文量
129
审稿时长
6-12 weeks
期刊介绍: Moscow University Physics Bulletin publishes original papers (reviews, articles, and brief communications) in the following fields of experimental and theoretical physics: theoretical and mathematical physics; physics of nuclei and elementary particles; radiophysics, electronics, acoustics; optics and spectroscopy; laser physics; condensed matter physics; chemical physics, physical kinetics, and plasma physics; biophysics and medical physics; astronomy, astrophysics, and cosmology; physics of the Earth’s, atmosphere, and hydrosphere.
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