(026) Application of Gelatin Sponge as a Hemostatic Agent in Penile Prosthesis Implantation

O. Mahmoud
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Abstract

Gelfoam® Sterile Compressed Sponge is a hemostatic that is directly applied to bleeding surfaces. This cost-effective hemostatic agent is prepared from purified porcine skin, Gelatin granules and Water for Injection. It is water insoluble, however is completely absorbed within 4–6 weeks with minimal scar formation. Gelfoam is available sterile for intra-operative use, and is applied in a multitude of surgical specialties. In this work, we demonstrate for the first time the of Gelfoam to minimize the risk of bleeding in penile prosthesis implantation. Eight cases received a three-piece inflatable implant (Rigicon Infla10®) through a peno-scrotal incision. Following cylinder insertion, corporotomies were closed by tying the stay sutures rather than water-tight sewing. Gelfoam was soaked in antibiotic-supplemented saline. Air bubbles were squeezed out followed by soaking. Gelfoam was then applied to the corporotomies, pump space and entry rout to the reservoir space. It was secured over the corporotomies by closing a pre-fashioned layer of Buck’s fascia. A suction drain was inserted. Mummy wrap was not used. Drain output was monitored and complications recorded. In two cases, drain output was an average of 80 cc’s in the first 24 hours, then 20 cc’s in the following 24 hours. However, in 6 cases, drain output was an average of 18 cc’s in the first 24 hours, mostly sero-sanguinous, then none in the following 24 hours. No cases of hematoma formation, infection, foreign body reaction, mass formation or hypersensitivity reaction were encountered. The initial results of the current small case series demonstrate that Gelfoam is well-tolerated in penile surgeries, with possible value at minimizing post-operative bleeding, encouraging a multi-center larger study. No.
(026) 阴茎假体植入术中应用海绵明胶作为止血剂
Gelfoam® 无菌压缩海绵是一种可直接用于出血表面的止血剂。这种经济高效的止血剂由纯化猪皮、明胶颗粒和注射用水制成。它不溶于水,但可在 4-6 周内完全吸收,疤痕形成极少。Gelfoam 可在无菌状态下用于术中,并可应用于多种外科专科。 在这项研究中,我们首次证明了在阴茎假体植入术中使用 Gelfoam 可以最大限度地降低出血风险。 八个病例通过阴茎阴囊切口接受了三件式充气假体(Rigicon Infla10®)。阴茎假体植入后,通过打结留置缝合而不是水密缝合来缝合阴茎体。用抗生素生理盐水浸泡气泡海绵。挤出气泡后再浸泡。然后在体部切口、泵间隙和通向储水池间隙的入口处涂抹海棉。在体部切口处封上一层预制的巴克筋膜,将其固定。插入抽吸引流管。没有使用木乃伊包裹。监测引流管的排出量并记录并发症。 在两个病例中,头 24 小时的引流液输出量平均为 80 毫升,随后 24 小时为 20 毫升。然而,在 6 个病例中,引流管在最初 24 小时内的平均输出量为 18 毫升,其中大部分为血清脓液,随后 24 小时内则没有输出。没有出现血肿形成、感染、异物反应、肿块形成或过敏反应。 目前这个小型病例系列的初步结果表明,Gelfoam 在阴茎手术中的耐受性良好,在最大限度减少术后出血方面可能具有价值,因此鼓励进行更大规模的多中心研究。 不
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