Early Onset Severe Aortic Stenosis Presenting with Recurrent Ventricular and Supraventricular Arrhythmia and Postoperative Stroke in a 44-year-old Man with Uncontrolled Rheumatoid Arthritis

Arvinjay A Bautista, Danilo S Kuizon
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Abstract

Calcific aortic stenosis is the most common aetiology of aortic stenosis and is mostly seen in older people. Systemic inflammatory diseases, such as rheumatoid arthritis (RA), are rarely associated with aortic stenosis in the literature. Uncontrolled systemic inflammation related to RA may lead to postoperative complications but this is not well documented. The patient in this case report was a 44-year-old man who had been diagnosed with RA that had been poorly controlled. He had a 7-month history of heart failure symptoms attributed to severe calcific aortic stenosis. He underwent surgical aortic valve replacement, but developed an acute cerebrovascular infarct 2 hours after surgery and recurrent unstable ventricular tachycardia on the first postoperative day warranting 15 synchronised cardioversions. RA is a rare antecedent cause of severe calcific aortic stenosis especially in younger people. Such a valvular complication associated with acute ischaemic stroke and ventricular arrhythmia warrants further study to provide optimal medical management, especially for patients with RA and early cardiovascular complications.
一名 44 岁类风湿性关节炎患者因早发重度主动脉瓣狭窄而出现复发性室性和室上性心律失常以及术后中风
钙化性主动脉瓣狭窄是主动脉瓣狭窄最常见的病因,多见于老年人。在文献中,类风湿性关节炎(RA)等全身性炎症性疾病很少与主动脉狭窄相关。与类风湿性关节炎相关的全身炎症未得到控制可能会导致术后并发症,但这方面的文献记载并不多。本病例报告中的患者是一名 44 岁的男性,被诊断出患有 RA,且病情控制不佳。他有 7 个月的心衰症状病史,原因是主动脉瓣严重钙化狭窄。他接受了主动脉瓣置换手术,但术后2小时出现急性脑血管梗塞,术后第一天反复出现不稳定室性心动过速,需要进行15次同步心脏电击。RA 是造成严重钙化性主动脉瓣狭窄的罕见先兆病因,尤其是在年轻人中。这种与急性缺血性中风和室性心律失常相关的瓣膜并发症值得进一步研究,以提供最佳的医疗管理,尤其是对患有 RA 和早期心血管并发症的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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