Expanded application of wearable cardioverter defibrillators beyond current guidelines: proposal for a European register explained through single clinical scenarios.

IF 2.8 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Veronica Buia, Francesco Ciotola, Dirk Bastian, Dorina Stangl, Janusch Walascheck, Harald Rittger, Laura Vitali-Serdoz
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引用次数: 0

Abstract

The wearable cardioverter defibrillator (WCD) is becoming a more and more widely used instrument for the prevention of sudden cardiac death of patients either with a secondary prevention implantable cardioverter defibrillator indication or with a transient high risk of sudden cardiac death. Although clinical practice has demonstrated a benefit of protecting patients for a period as long as 3-6 months with such devices, the current European guidelines concerning ventricular arrhythmias and sudden cardiac death are still extremely restrictive in the patient selection in part because of the costs derived from such a prevention device, in part because of the lack of robust randomised trials.To illustrate expanded use cases for the WCD, four real-life clinical cases are presented where patients received the device slightly outside the established guidelines. These cases demonstrate the broader utility of WCDs in situations involving acute myocarditis, thyrotoxicosis, pre-excited atrial fibrillation and awaiting staging/prognosis of a lung tumour. The findings prompt expansion of the existing guidelines for WCD use to efficiently protect more patients whose risk of arrhythmic cardiac death is transient or uncertain. This could be achieved by establishing a European register of the patients who receive a WCD for further analysis.

可穿戴式心律转复除颤器在现行指南之外的扩展应用:通过单一临床场景解释欧洲登记册的建议。
可穿戴式心律转复除颤器(WCD)正在成为一种越来越广泛的预防心脏性猝死的工具,它适用于有植入式心律转复除颤器二级预防指征或有一过性心脏性猝死高风险的患者。虽然临床实践已经证明,使用这种设备可以在长达 3-6 个月的时间内保护患者,但目前欧洲有关室性心律失常和心脏性猝死的指南在患者选择方面仍有极大的限制,部分原因是这种预防设备的成本较高,部分原因是缺乏可靠的随机试验。这些病例展示了 WCD 在急性心肌炎、甲状腺毒症、预激性心房颤动和等待肺部肿瘤分期/预后等情况下的广泛用途。这些发现促使我们扩大现有的 WCD 使用指南,以有效保护更多心律失常性心源性死亡风险短暂或不确定的患者。要做到这一点,可以在欧洲建立一个接受 WCD 患者登记册,以便进行进一步分析。
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来源期刊
Open Heart
Open Heart CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
4.60
自引率
3.70%
发文量
145
审稿时长
20 weeks
期刊介绍: Open Heart is an online-only, open access cardiology journal that aims to be “open” in many ways: open access (free access for all readers), open peer review (unblinded peer review) and open data (data sharing is encouraged). The goal is to ensure maximum transparency and maximum impact on research progress and patient care. The journal is dedicated to publishing high quality, peer reviewed medical research in all disciplines and therapeutic areas of cardiovascular medicine. Research is published across all study phases and designs, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Opinionated discussions on controversial topics are welcomed. Open Heart aims to operate a fast submission and review process with continuous publication online, to ensure timely, up-to-date research is available worldwide. The journal adheres to a rigorous and transparent peer review process, and all articles go through a statistical assessment to ensure robustness of the analyses. Open Heart is an official journal of the British Cardiovascular Society.
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