CeO2 nanoparticles and cerium species as antiviral agents: Critical review

European Journal of Medicinal Chemistry Reports Pub Date : 2024-03-02 DOI:10.1016/j.ejmcr.2024.100141

Alexander B. Shcherbakov

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Abstract

Viral infections account for a large proportion of the total number of fatal diseases and require close attention from the international public health community. The COVID-19 pandemic has highlighted problems in medicine and healthcare related to the search for effective substances for the prevention, diagnosis and treatment of viral infections. According to many scientific studies, cerium species are very promising biomedical materials for combatting viral infections and have shown encouraging results in killing viruses on non-living objects, reducing viral load both in vitro and in vivo, relieving symptoms and reducing the consequences of viral diseases. This review critically examines the current level of knowledge on cerium species and their practical applications, with a focus on CeO₂ nanoparticles (CeNPs). This review also seeks to assess the prospects for their development and use in antiviral theranostics.

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作为抗病毒剂的 CeO2 纳米粒子和铈物种：评论

病毒感染在致命疾病总数中占很大比例，需要国际公共卫生界密切关注。COVID-19 大流行凸显了医学和保健领域在寻找预防、诊断和治疗病毒感染的有效物质方面存在的问题。根据许多科学研究，铈类物质是非常有前途的抗病毒感染生物医学材料，在杀死非生物物体上的病毒、减少体外和体内病毒载量、缓解症状和减轻病毒性疾病的后果方面都取得了令人鼓舞的成果。这篇综述以二氧化铈纳米粒子（CeNPs）为重点，批判性地研究了当前有关铈物种及其实际应用的知识水平。本综述还试图评估其在抗病毒治疗学中的开发和应用前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Medicinal Chemistry Reports

CiteScore

4.50

自引率

0.00%

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