Influence of the dilution method on the intraocular duration of C3F8 in vitrectomy for macular hole: a randomized clinical trial.

IF 1.1 4区医学 Q3 OPHTHALMOLOGY

Arquivos brasileiros de oftalmologia Pub Date : 2024-03-04 eCollection Date: 2024-01-01 DOI:10.5935/0004-2749.2022-0336

Alexandre Paashaus da Costa Pinto, Daniel Tenório Camelo Soares, Marília Rocha Costa, Rodrigo Pessoa Cavalcanti Lira

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引用次数: 0

Abstract

Purpose: To compare the injection of small amounts of undiluted C3F8 with the traditional gas injection in vitrectomy for macular hole treatment.

Methods: This clinical trial included 26 individuals divided into two groups. Group 1 received an intravitreal injection of 0.9-1.0 mL of 100% C3F8, and Group 2 received 15-20 mL of 20% C3F8.

Results: The median intraocular gas duration was 31 days in Group 1 and 34 in Group 2. The median letter gains in corrected distance visual acuity for the 26th postoperative week were 20 letters in Group 1 and 12.5 in Group 2. The median intraocular pressure was normal in both groups. Primary anatomical success was 11/13 in both groups.

Conclusions: The use of C3F8 gas in a small undiluted volume is an alternative that slightly reduces the duration of the gas without negatively affecting the anatomical and visual response.

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稀释法对黄斑孔玻璃体切除术中 C3F8 眼内持续时间的影响：随机临床试验。

目的：比较在玻璃体切除术中注射少量未稀释的 C3F8 与传统气体注射治疗黄斑孔的效果：这项临床试验包括 26 人，分为两组。第一组接受 0.9-1.0 mL 100%的 C3F8 玻璃体内注射，第二组接受 15-20 mL 20%的 C3F8 玻璃体内注射：第一组和第二组的中位眼内气体持续时间分别为 31 天和 34 天，术后第 26 周矫正远视力的中位增益分别为 20 个字母和 12.5 个字母，两组的中位眼压均正常。两组的初次解剖成功率均为 11/13：结论：使用未稀释的小体积 C3F8 气体是一种替代方法，它可以略微缩短气体持续时间，而不会对解剖和视觉反应产生负面影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arquivos brasileiros de oftalmologia OPHTHALMOLOGY-

CiteScore

1.60

自引率

0.00%

发文量

200

审稿时长

6-12 weeks

期刊介绍： The ABO-ARQUIVOS BRASILEIROS DE OFTALMOLOGIA (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - electronic version), the official bimonthly publication of the Brazilian Council of Ophthalmology (CBO), aims to disseminate scientific studies in Ophthalmology, Visual Science and Health public, by promoting research, improvement and updating of professionals related to the field.