Review of Herbal Medicinal Plants Used in the Management of Cancers in the East Africa Region from 2019 to 2023.

IF 2.9 3区医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE

Integrative Cancer Therapies Pub Date : 2024-01-01 DOI:10.1177/15347354241235583

Ali Kudamba, Josephine N Kasolo, Godfrey S Bbosa, Allan Lugaajju, Henry Wabinga, Hussein M Kafeero, Jamilu E Ssenku, Shaban O Alemu, Abdul Walusansa, Nixon Niyonzima, Haruna Muwonge

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引用次数: 0

Abstract

Background: In the East African region, herbal plants are essential in the treatment and control of cancer. Given the diverse ecological and cultural makeup of the regional states, it is likely that different ethnic groups will use the same or different plants for the same or different diseases. However, since 2019, this has not been compiled into a single study.

Purpose: The study aimed to compile and record the medicinal plants utilized in East Africa from April 2019 to June 2023 to treat various cancer types.

Materials and methods: The study examined 13 original studies that included ethnobotanical research conducted in East Africa. They were retrieved from several internet databases, including Google Scholar, Scopus, PubMed/Medline, Science Direct, and Research for Life. The study retrieved databases on plant families and species, plant parts used, preparation methods and routes of administration, and the country where the ethnobotanical field surveys were conducted. Graphs were produced using the GraphPad Prism 8.125 program (GraphPad Software, Inc., San Diego, CA). Tables and figures were used to present the data, which had been condensed into percentages and frequencies.

Results: A total of 105 different plant species from 45 different plant families were identified, including Asteraceae (14), Euphorbiaceae (12), Musaceae (8), and Apocynaceae (7). Uganda registered the highest proportion (46% of the medicinal plants used). The most commonly mentioned medicinal plant species in cancer management was Prunus africana. Herbs (32%), trees and shrubs (28%), and leaves (45%) constituted the majority of herbal remedies. Most herbal remedies were prepared by boiling (decoction) and taken orally (57%).

Conclusion: East Africa is home to a wide variety of medicinal plant species that local populations and herbalists, or TMP, frequently use in the treatment of various types of cancer. The most frequently used families are Asteraceae and Euphorbiaceae, with the majority of species being found in Uganda. The most frequently utilized plant species is Prunus africana. Studies on the effectiveness of Prunus africana against other malignancies besides prostate cancer are required.

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2019年至2023年东非地区用于治疗癌症的草本药用植物回顾。

背景：在东非地区，草本植物对治疗和控制癌症至关重要。由于该地区各州的生态和文化构成各不相同，不同的种族群体很可能会使用相同或不同的植物来治疗相同或不同的疾病。然而，自 2019 年以来，这方面的情况尚未汇编成一份研究报告。目的：本研究旨在汇编和记录 2019 年 4 月至 2023 年 6 月期间东非地区用于治疗各种癌症的药用植物：本研究审查了 13 项原创研究，其中包括在东非开展的人种植物学研究。这些研究是从多个互联网数据库中检索的，包括谷歌学术、Scopus、PubMed/Medline、Science Direct 和 Research for Life。研究检索了有关植物科和种、所用植物部位、制备方法和给药途径以及进行民族植物学实地调查的国家的数据库。使用 GraphPad Prism 8.125 程序（GraphPad Software, Inc.）数据用表格和数字表示，并浓缩成百分比和频率：共鉴定出 45 个不同植物科的 105 种不同植物，包括菊科（14 种）、大戟科（12 种）、蕈科（8 种）和天南星科（7 种）。乌干达的比例最高（占所用药用植物的 46%）。在癌症治疗中最常提及的药用植物种类是非洲李（Prunus africana）。草药（32%）、乔木和灌木（28%）以及树叶（45%）占草药疗法的大多数。大多数草药通过煮沸（煎煮）后口服（57%）：结论：东非是多种药用植物的故乡，当地居民和草药医生（TMP）经常使用这些植物治疗各种癌症。最常使用的植物科是菊科和大戟科，大部分物种在乌干达发现。最常用的植物物种是非洲李。除前列腺癌外，还需要研究非洲李对其他恶性肿瘤的疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Integrative Cancer Therapies 医学-全科医学与补充医学

CiteScore

4.80

自引率

3.40%

发文量

审稿时长

>12 weeks

期刊介绍： ICT is the first journal to spearhead and focus on a new and growing movement in cancer treatment. The journal emphasizes scientific understanding of alternative medicine and traditional medicine therapies, and their responsible integration with conventional health care. Integrative care includes therapeutic interventions in diet, lifestyle, exercise, stress care, and nutritional supplements, as well as experimental vaccines, chrono-chemotherapy, and other advanced treatments. Contributors are leading oncologists, researchers, nurses, and health-care professionals.