Symptom-specific improvement across therapies and their putative mediators: A mediation network intervention analysis.

IF 2.6 1区心理学 Q2 PSYCHOLOGY, CLINICAL

Psychotherapy Research Pub Date : 2025-04-01 Epub Date: 2024-03-03 DOI:10.1080/10503307.2024.2320349

Jette Echterhoff, Levente Kriston, Jan Philipp Klein, Martin Härter, Elisabeth Schramm, Lea Schumacher

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引用次数: 0

Abstract

Objective: We evaluated differential treatment effects on specific symptoms and their mediators for Cognitive Behavioral Analysis System of Psychotherapy (CBASP) and Supportive Psychotherapy (SP) in persistently depressed patients.

Method: We conducted a Bayesian mediation network intervention analysis with data from a randomized controlled trial comparing CBASP and SP. Three networks were calculated to investigate (1) differential treatment effects on specific symptoms, (2) differential treatment effects on the potential mediators interpersonal problems and social functioning, and (3) associations between change in symptoms and change in the potential mediators.

Results: First, we found no evidence that CBASP more strongly improves most depressive symptoms specifically, except minimal evidence of symptom-specific effects on sleeping problems and self-esteem. Second, no and minimal evidence for differential treatment effects on interpersonal problems and social functioning was shown, respectively. Third, interpersonal problems and social functioning were strongly related to depressive symptoms.

Conclusion: While CBASP showed superior treatment effects for overall symptom severity, this treatment might not be superior in improving specific symptoms and the potential mediators interpersonal problems and social functioning. Still, interpersonal problems and social functioning seem to play an important role for depression symptoms. Future research needs to further investigate potential working mechanisms of CBASP.Trial registration: ClinicalTrials.gov identifier: NCT00970437.

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不同疗法对症状的改善及其潜在的中介因素：中介网络干预分析。

目的我们评估了认知行为分析系统心理疗法（CBASP）和支持性心理疗法（SP）对持续性抑郁症患者特定症状及其中介因素的不同治疗效果：我们利用一项比较 CBASP 和 SP 的随机对照试验数据进行了贝叶斯中介网络干预分析。我们计算了三个网络，以研究（1）对特定症状的不同治疗效果，（2）对潜在中介因素人际问题和社会功能的不同治疗效果，以及（3）症状变化与潜在中介因素变化之间的关联：首先，我们没有发现 CBASP 能更有力地改善大多数抑郁症状的具体证据，只有极少数证据表明其对睡眠问题和自尊的具体症状有影响。其次，在人际关系问题和社会功能方面，分别没有和只有极少的证据表明治疗效果不同。第三，人际关系问题和社会功能与抑郁症状密切相关：结论：虽然 CBASP 对总体症状严重程度的治疗效果较好，但在改善特定症状以及潜在的中介因素人际问题和社会功能方面可能并不占优。不过，人际关系问题和社会功能似乎对抑郁症状起着重要作用。未来的研究需要进一步探讨CBASP的潜在工作机制：试验注册：ClinicalTrials.gov identifier：NCT00970437.

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psychotherapy Research PSYCHOLOGY, CLINICAL-

CiteScore

7.80

自引率

10.30%

发文量

期刊介绍： Psychotherapy Research seeks to enhance the development, scientific quality, and social relevance of psychotherapy research and to foster the use of research findings in practice, education, and policy formulation. The Journal publishes reports of original research on all aspects of psychotherapy, including its outcomes, its processes, education of practitioners, and delivery of services. It also publishes methodological, theoretical, and review articles of direct relevance to psychotherapy research. The Journal is addressed to an international, interdisciplinary audience and welcomes submissions dealing with diverse theoretical orientations, treatment modalities.