Cost-utility analysis of transitional care services for older inpatients with chronic obstructive pulmonary disease (COPD) in Korea.

IF 1.7 4区 医学 Q3 HEALTH POLICY & SERVICES
Yu Seong Hwang, Woo Jin Kim, Tae Hyun Kim, Yukyung Park, Su Mi Jung, Heui Sug Jo
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Abstract

Background: Chronic obstructive pulmonary disease (COPD) is associated with a high readmission rate and poses a significant disease burden. South Korea initiated pilot projects on transitional care services (TCS) to reduce readmissions. However, evidence from cost-effectiveness analyses remains undiscovered. This study aimed to evaluate the cost-effectiveness of TCS in patients with COPD from the healthcare system' perspective.

Method: A cost-utility analysis was conducted using a Markov model containing six components of possible medical use after discharge. Transition probabilities and medical costs were extracted from the National Health Insurance Service Senior Cohort (NHIS-SC), and utility data were obtained from published literature. Sensitivity analyses were performed to test the robustness of the results.

Results: Conducting TCS produced an incremental quality-adjusted life years gain of 0.231, 0.275, 0.296 for those in their 60s, 70s, and 80s, respectively, and cost savings of $225.16, $1668, and $2251.64 for those in their 60s, 70s, and 80s, respectively, per patient over a 10-year time horizon. The deterministic sensitivity analysis indicated that the TCS cost and the cost of readmission by other diseases immensely impact the results. The probabilistic sensitivity analyses showed that the probability that the incremental cost-effectiveness ratio is below $23,050 was over 85%, 93%, and 97% for those in the 60s, 70s, and 80s, respectively.

Conclusions: TCS was the dominant option compared to usual care. However, it is advantageous to the healthcare budget preferentially consider patients aged over 70 years with severe TCS symptoms. In addition, it is essential to include the management of underlying comorbidities in TCS intervention.

Trial registration: Clinical Research Information Service (CRIS), KCT0007937. Registered on 24 November 2022.

韩国老年慢性阻塞性肺病(COPD)住院患者过渡护理服务的成本效用分析。
背景:慢性阻塞性肺病(COPD)的再入院率很高,造成了严重的疾病负担。韩国启动了过渡性护理服务(TCS)试点项目,以减少再入院率。然而,成本效益分析的证据仍未被发现。本研究旨在从医疗系统的角度评估慢性阻塞性肺病患者过渡护理服务的成本效益:方法:使用马尔可夫模型进行成本效用分析,该模型包含出院后可能使用医疗服务的六个组成部分。过渡概率和医疗费用来自国民健康保险服务老年队列(NHIS-SC),效用数据来自公开发表的文献。进行了敏感性分析以检验结果的稳健性:在 10 年的时间跨度内,对 60、70 和 80 岁的患者进行全套护理服务可使每位患者的质量调整生命年分别增加 0.231、0.275 和 0.296,成本分别节省 225.16、1668 和 2251.64 美元。确定性敏感性分析表明,TCS 成本和其他疾病的再入院成本对结果影响巨大。概率敏感性分析表明,60、70 和 80 岁患者的增量成本效益比低于 23,050 美元的概率分别超过 85%、93% 和 97%:与常规护理相比,TCS 是最主要的选择。然而,优先考虑 70 岁以上有严重 TCS 症状的患者对医疗预算是有利的。此外,在TCS干预中还必须包括对潜在合并症的管理:临床研究信息服务(CRIS),KCT0007937。注册日期:2022 年 11 月 24 日。
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来源期刊
Cost Effectiveness and Resource Allocation
Cost Effectiveness and Resource Allocation HEALTH POLICY & SERVICES-
CiteScore
3.40
自引率
4.30%
发文量
59
审稿时长
34 weeks
期刊介绍: Cost Effectiveness and Resource Allocation is an Open Access, peer-reviewed, online journal that considers manuscripts on all aspects of cost-effectiveness analysis, including conceptual or methodological work, economic evaluations, and policy analysis related to resource allocation at a national or international level. Cost Effectiveness and Resource Allocation is aimed at health economists, health services researchers, and policy-makers with an interest in enhancing the flow and transfer of knowledge relating to efficiency in the health sector. Manuscripts are encouraged from researchers based in low- and middle-income countries, with a view to increasing the international economic evidence base for health.
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