Biodegradable biliary stents placement using a "kissing-stent" technique for management of a recalcitrant stricture post-live donor liver transplant.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-03-01 DOI:10.1111/petr.14725

Aleena Malik, Vicky L Ng, Blayne A Sayed, Asad Siddiqui, Dimitri A Parra

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引用次数: 0

Abstract

Background: Biliary complications are common in pediatric liver transplant. Strictures resistant to interventional radiology procedures can be extremely challenging to manage and may result in the need of surgery or retransplantation.

Methods: This case report illustrates the use of biodegradable stents post left lateral segment live donor liver transplant in a pediatric patient with a recalcitrant chronic stricture of the biliary-enteric anastomosis. The patient developed a high stricture requiring multiple interventions and eventual access of both the segment II and segment III ducts of the graft.

Results: To ensure adequate biliary drainage, two biodegradable stents were deployed using a "kissing-stent" technique. The stents were successfully deployed and allowed the patient to remain free from an internal-external biliary drain for 11 months, with eventual redeployment of an additional biodegradable stent.

Conclusion: In patients with recalcitrant stenosis of the biliary anastomosis, biodegradable stents may provide durable drainage, optimizing graft function and delaying retransplantation in addition to keeping patients without external devices, thus improving quality of life.

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利用 "吻合支架 "技术放置生物可降解胆道支架，治疗活体肝移植后顽固性狭窄。

背景：胆道并发症在小儿肝移植中很常见。对介入放射学手术有抵抗力的胆道狭窄极难处理，可能导致需要手术或再次移植：本病例报告说明了在左侧段活体肝移植术后使用生物可降解支架治疗胆肠吻合口顽固性慢性狭窄的儿科患者的情况。该患者的胆肠吻合口出现高度狭窄，需要多次介入治疗，并最终进入移植物的 II 段和 III 段管道：为确保充分的胆道引流，采用 "吻合支架 "技术放置了两个生物可降解支架。结果：为确保胆道引流通畅，采用 "吻合支架 "技术放置了两个可降解支架。支架放置成功后，患者在11个月的时间里一直没有使用胆道内外引流管，最终又重新放置了一个可降解支架：结论：对于胆道吻合口狭窄顽固的患者，生物可降解支架可提供持久的引流，优化移植物的功能，推迟再次移植的时间，此外还能让患者无需外部装置，从而提高生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.