The relationship between depression, anxiety and lower urinary tract symptoms in men

IF 2.7 2区医学 Q2 UROLOGY & NEPHROLOGY

Prostate International Pub Date : 2024-06-01 DOI:10.1016/j.prnil.2024.02.002

Yu Seob Shin , Kiran Kumar Soni , Dong Yun Lee , Sung Chul Kam

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引用次数: 0

Abstract

Purpose

Patients with lower urinary tract symptoms (LUTS) often experience comorbid depression and anxiety, yet the mechanisms underlying this association remain incompletely understood. This prospective study aimed to investigate the relationship between depression, anxiety, and LUTS in men.

Materials and methods

A prospective study was conducted with 350 male patients who underwent urologic examinations at our institution from January 2021 to December 2021. Of these, 131 patients meeting the inclusion criteria were included. Various questionnaires, including the International Prostate Symptom Score (IPSS) and the Hospital Anxiety and Depression Scale (HADS), as well as LUTS examinations (prostate-specific antigen test, transrectal ultrasonography, and urine flowmetry), were administered.

Results

Among the 350 patients, 131 were included in the analysis, with an average age of 58.0 ± 13.69 years. The total IPSS was 18.0 ± 8.69, with the average voiding symptom score at 8.7 ± 5.19 and the average storage symptom score at 6.0 ± 3.27. Both anxiety and depression were found to be correlated with LUTS (P < 0.05). After adjusting for age, hypertension, and diabetes, anxiety (but not depression) was significantly associated with LUTS based on regression analysis.

Conclusion

Men with LUTS are more likely to experience anxiety. Therefore, it is essential to assess and address anxiety when managing men with LUTS.

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男性抑郁、焦虑与下尿路症状之间的关系

下尿路症状（LUTS）患者通常会合并抑郁和焦虑，但这种关联的内在机制仍不完全清楚。这项前瞻性研究旨在探讨男性抑郁、焦虑与下尿路症状之间的关系。本研究对 2021 年 1 月至 2021 年 12 月期间在我院接受泌尿科检查的 350 名男性患者进行了前瞻性研究。其中，131 名患者符合纳入标准。研究人员进行了各种问卷调查，包括国际前列腺症状评分（IPSS）和医院焦虑抑郁量表（HADS），以及前列腺液排泄障碍检查（前列腺特异性抗原检测、经直肠超声检查和尿流测定）。在 350 名患者中，有 131 人被纳入分析，平均年龄为 58.0 ± 13.69 岁。IPSS 总分为（18.0 ± 8.69）分，排尿症状平均分为（8.7 ± 5.19）分，储尿症状平均分为（6.0 ± 3.27）分。焦虑和抑郁均与 LUTS 相关（P < 0.05）。在对年龄、高血压和糖尿病进行调整后，根据回归分析，焦虑（而非抑郁）与 LUTS 显著相关。患有 LUTS 的男性更有可能经历焦虑。因此，在对患有 LUTS 的男性进行治疗时，评估和解决焦虑问题至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Prostate International Medicine-Urology

CiteScore

4.40

自引率

26.70%

发文量

审稿时长

35 days

期刊介绍： Prostate International (Prostate Int, PI), the official English-language journal of Asian Pacific Prostate Society (APPS), is an international peer-reviewed academic journal dedicated to basic and clinical studies on prostate cancer, benign prostatic hyperplasia, prostatitis, and ...