The effects of chlorotoxin and its derivatives on glioma cells: a systematic review of in vitro studies

IF 3.3 4区医学 Q2 TOXICOLOGY

Toxin Reviews Pub Date : 2024-02-28 DOI:10.1080/15569543.2024.2321473

Shahrzad Molavinia, Maryam Salehcheh, Masoumeh Baradaran, Mohammad Ali Karimi, Gholamreza Pirmoradi, Elaheh Mohammadi

引用次数: 0

Abstract

Chlorotoxin (CTX), a peptide derived from scorpion venom, is used to detect chloride channels. CTX targets cancer cells like glioblastoma (GBM) via GBM-specific chloride channels. CTX-based uses in...

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氯毒素及其衍生物对胶质瘤细胞的影响：体外研究的系统回顾

氯毒素（CTX）是从蝎毒中提取的一种多肽，可用于检测氯离子通道。CTX 可通过神经胶质母细胞瘤（GBM）特异性氯离子通道靶向神经胶质母细胞瘤（GBM）等癌细胞。以 CTX 为基础的...

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Toxin Reviews 医学-毒理学

CiteScore

6.80

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Toxin Reviews provides an international forum for publishing state-of-the-art reviews and guest-edited single topic special issues covering the multidisciplinary research in the area of toxins derived from animals, plants and microorganisms. Our aim is to publish reviews that are of broad interest and importance to the toxinology as well as other life science communities. Toxin Reviews aims to encourage scientists to highlight the contribution of toxins as research tools in deciphering molecular and cellular mechanisms, and as prototypes of therapeutic agents. Reviews should emphasize the role of toxins in enhancing our fundamental understanding of life sciences, protein chemistry, structural biology, pharmacology, clinical toxinology and evolution. Prominence will be given to reviews that propose new ideas or approaches and further the knowledge of toxinology.