[Cardiogenetics in Germany- a view and review].

Q4 Medicine
E Schulze-Bahr
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引用次数: 0

Abstract

The development of the cardiogenetics field in Germany has been increasing since the mid-1990s with many national contributions, some of them were really important and groundbreaking. The starting point was and still is the patient and his family, e.g. with a familial form of arrhythmia or cardiomyopathy, the clarification of the genetic cause and the personalized treatment of those being affected. The scientific, always translationally oriented interest in identifying a causative gene and uncovering the underlying pathomechanisms has led to notable contributions for Brugada syndrome, short QT syndrome and cardiac conduction disorders or sinus node dysfunction, but also in DCM or ARVC. What is important, however, is always the way back (bench > bed side): implementation of national and international recommendations for cardiogenetic diagnostics in daily cardiological routine and the personalized care and therapy of those being affected.

[德国的心脏遗传学--观点与回顾]。
自 20 世纪 90 年代中期以来,德国在心脏遗传学领域的发展日新月异,做出了许多国家级的贡献,其中不乏真正重要的开创性成果。过去和现在的出发点都是患者及其家庭,例如家族性心律失常或心肌病患者,明确遗传原因并为患者提供个性化治疗。科学界对确定致病基因和揭示潜在病理机制的兴趣始终以转化为导向,这不仅为 Brugada 综合征、短 QT 综合征和心脏传导障碍或窦房结功能障碍做出了显著贡献,也为 DCM 或 ARVC 做出了显著贡献。然而,重要的始终是回归之路(工作台 > 床边):在日常心脏病学工作中落实国家和国际有关心脏遗传学诊断的建议,并为受影响者提供个性化护理和治疗。
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来源期刊
Herzschrittmachertherapie und Elektrophysiologie
Herzschrittmachertherapie und Elektrophysiologie Medicine-Cardiology and Cardiovascular Medicine
CiteScore
1.10
自引率
0.00%
发文量
76
期刊介绍: Mit wissenschaftlichen Original- und Übersichtsarbeiten, Berichten über moderne Operationstechniken und experimentelle Methoden ist die Zeitschrift Herzschrittmachertherapie + Elektrophysiologie ein Diskussionsforum für Themen wie: - Zelluläre Elektrophysiologie - Theoretische Elektrophysiologie - Klinische Elektrophysiologie - Angewandte Herzschrittmachertherapie - Bradykarde und tachykarde Herzrhythmusstörungen - Plötzlicher Herztod und Risikostratifikation - Elektrokardiographie - Elektromedizinische Technologie - Experimentelle und klinische Pharmakologie - Herzchirurgie bei Herzrhythmusstörungen Mitteilungen der Arbeitsgruppen Herzschrittmacher und Arrhythmie der Deutschen Gesellschaft für Kardiologie - Herz und Kreislaufforschung e.V. (DGK) sowie Stellungnahmen und praktische Hinweise runden das breite Spektrum dieser Zeitschrift ab. Interessensgebiete: Kardiologie, Herzschrittmachertherapie, Herzschrittmachertechnologie, klinische Elektrophysiologie
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