A Randomised Controlled Trial Evaluating the Aesthetic Outcomes of Oncoplasty vs. Simple Closure and 1- vs. 2-cm Excision Margin for Early Breast Cancer

IF 0.4 4区 医学 Q4 SURGERY
Shivangi Saha, Dhritiman Maitra, Maneesh Singhal, Seenu Vuthaluru, Anita Dhar, Piyush Mishra, Smriti Hari, Kamal Kataria, Anurag Srivastava, R. M. Pandey
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引用次数: 0

Abstract

Breast conservation surgery is the standard of care for patients with early breast cancer. Although most surgeons perform oncoplasty for closure of defect, there is no randomised evidence for its favour as compared to simple closure of breast defect. We compared the cosmetic outcomes of patients treated by oncoplasty versus simple closure with 1-cm vs. 2-cm margin of excision. One hundred and four patients with breast cancer were randomised to four groups: excision with 1-cm margin with simple closure or excision with 2-cm margin with simple closure; excision with 1-cm margin and oncoplasty; and excision with 2-cm margin oncoplasty. Fifty-two patients underwent oncoplasty and 52 patients had simple closure of breast defect. There was no significant difference in the cosmetic outcomes in patients undergoing oncoplasty compared to simple closure. Excision with 2-cm margin compared to 1 cm did not worsen the cosmetic outcome. The margin positivity and re-excision rates were higher with 1-cm margin and oncoplastic closure group (p-value 0.018). There was no significant difference in complications between oncoplasty compared to simple closure, and 1-cm vs. 2-cm margin of excision. Simple closure demonstrated similar cosmesis as compared to oncoplasty.

Abstract Image

一项随机对照试验,评估早期乳腺癌的肿瘤成形术与简单闭合术、1 厘米切除边缘与 2 厘米切除边缘的美学效果
保乳手术是早期乳腺癌患者的标准治疗方法。虽然大多数外科医生都会采用乳房整形术来缝合乳房缺损,但与单纯乳房缺损缝合术相比,目前还没有随机证据表明乳房整形术更受青睐。我们比较了乳房整形术与单纯闭合术(切除边缘为 1 厘米与 2 厘米)对患者美容效果的影响。144 名乳腺癌患者被随机分为四组:切除 1 厘米边缘并简单缝合或切除 2 厘米边缘并简单缝合;切除 1 厘米边缘并进行肿瘤成形术;切除 2 厘米边缘并进行肿瘤成形术。52 名患者进行了肿瘤成形术,52 名患者进行了乳房缺损简单闭合术。与单纯闭合相比,接受肿瘤成形术的患者在美容效果上没有明显差异。边缘为 2 厘米的切除术与边缘为 1 厘米的切除术相比,美容效果并没有恶化。边缘1厘米和肿瘤整形闭合组的边缘阳性率和再次切除率更高(P值为0.018)。在并发症方面,肿瘤成形术与单纯闭合术、1 厘米切除边缘与 2 厘米切除边缘之间没有明显差异。与肿瘤整形术相比,单纯闭合术显示出相似的外观。
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来源期刊
CiteScore
0.60
自引率
25.00%
发文量
412
审稿时长
6-12 weeks
期刊介绍: The Indian Journal of Surgery is the official publication of the Association of Surgeons of India that considers for publication articles in all fields of surgery. Issues are published bimonthly in the months of February, April, June, August, October and December. The journal publishes Original article, Point of technique, Review article, Case report, Letter to editor, Teachers and surgeons from the past - A short (up to 500 words) bio sketch of a revered teacher or surgeon whom you hold in esteem and Images in surgery, surgical pathology, and surgical radiology. A trusted resource for peer-reviewed coverage of all types of surgery Provides a forum for surgeons in India and abroad to exchange ideas and advance the art of surgery The official publication of the Association of Surgeons of India 92% of authors who answered a survey reported that they would definitely publish or probably publish in the journal again The Indian Journal of Surgery offers peer-reviewed coverage of all types of surgery. The Journal publishes Original articles, Points of technique, Review articles, Case reports, Letters, Images and brief biographies of influential teachers and surgeons. The Journal spans General Surgery, Pediatric Surgery, Neurosurgery, Plastic Surgery, Cardiothoracic Surgery, Vascular Surgery, Rural Surgery, Orthopedic Surgery, Urology, Surgical Oncology, Radiology, Anaesthesia, Trauma Services, Minimal Access Surgery, Endocrine Surgery, GI Surgery, ENT, Colorectal Surgery, surgical practice and research. The Journal provides a forum for surgeons from India and abroad to exchange ideas, to propagate the advancement of science and the art of surgery and to promote friendship among surgeons in India and abroad. This has been a trusted platform for surgons in communicating up-to-date scientific informeation to the community.
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