Decline in case rates of youth onset type 2 diabetes in year three of the COVID-19 pandemic.

IF 1.3 4区医学 Q4 ENDOCRINOLOGY & METABOLISM

Journal of Pediatric Endocrinology & Metabolism Pub Date : 2024-02-28 Print Date: 2024-04-25 DOI:10.1515/jpem-2023-0498

Ahlee Kim, David Geller, Hyojin Min, Brian Miyazaki, Jennifer Raymond, Alaina P Vidmar, Rachel Zipursky, Lily C Chao

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引用次数: 0

Abstract

Objectives: To determine changes in case rates of youth onset type 2 diabetes in the three years following the COVID-19 pandemic.

Methods: A single-center, retrospective medical record review was conducted for patients newly diagnosed with T2D between 3/1/18 and 2/28/23 at a pediatric tertiary care center. The number of patients referred to CHLA with a T2D diagnosis date between 3/1/2020 and 2/28/2023 was compared to historical rates between 3/1/2018 and 2/29/2020. χ² or Fisher's exact test was used to compare categorical variables between each year and 2019.

Results: Compared to prepandemic baseline (3/1/19-2/29/20, 11.8±3.7 cases/month), there was a significant increase in new T2D monthly case rates in pandemic year 1 (3/1/20-2/28/21, 20.1±6.0 cases/month, 171 %, p=0.005) and pandemic year 2 (3/1/21-2/28/22, 25.9±8.9 cases/month, 221 %, p=0.002). Case rates declined in pandemic year 3 to 14.5±4.1 cases/month (3/1/22-2/28/23, p=0.43). Compared to prepandemic year 1, the frequency of DKA at diagnosis was higher in pandemic year 1 (13.3 vs. 5.0 %, p=0.009). The DKA rate in pandemic years 2 (6.8 %) and 3 (3.4 %) were comparable to prepandemic year 1 (p=0.53 and 0.58, respectively).

Conclusions: Youth onset type 2 diabetes cases and DKA rates in year 3 of the pandemic have returned to prepandemic level.

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在 COVID-19 大流行的第三年，青年 2 型糖尿病发病率有所下降。

目标：确定 COVID-19 大流行后三年内青少年 2 型糖尿病发病率的变化：确定 COVID-19 大流行后三年内青少年 2 型糖尿病发病率的变化：对一家儿科三级医疗中心在 18 年 1 月 3 日至 23 年 2 月 28 日期间新诊断出的 T2D 患者进行了单中心回顾性病历审查。将诊断日期在2020年1月3日至2023年2月28日之间、转诊至CHLA的T2D患者人数与2018年1月3日至2020年2月29日之间的历史比率进行了比较。采用χ2或费雪精确检验比较每年与2019年之间的分类变量：与大流行前基线（3/1/19-2/29/20，11.8±3.7例/月）相比，大流行第1年（3/1/20-2/28/21，20.1±6.0例/月，171%，P=0.005）和大流行第2年（3/1/21-2/28/22，25.9±8.9例/月，221%，P=0.002）的T2D月新增病例率显著增加。病例率在大流行第 3 年下降到 14.5±4.1 例/月（3/1/22-2/28/23，p=0.43）。与大流行前的第 1 年相比，大流行第 1 年诊断时出现 DKA 的频率更高（13.3% 对 5.0%，P=0.009）。大流行第二年（6.8%）和第三年（3.4%）的DKA发生率与大流行前一年相当（p=0.53和0.58）：结论：大流行第 3 年的青年 2 型糖尿病病例和 DKA 发生率已恢复到大流行前的水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Pediatric Endocrinology & Metabolism 医学-内分泌学与代谢

CiteScore

2.70

自引率

7.10%

发文量

176

审稿时长

3-6 weeks

期刊介绍： The aim of the Journal of Pediatric Endocrinology and Metabolism (JPEM) is to diffuse speedily new medical information by publishing clinical investigations in pediatric endocrinology and basic research from all over the world. JPEM is the only international journal dedicated exclusively to endocrinology in the neonatal, pediatric and adolescent age groups. JPEM is a high-quality journal dedicated to pediatric endocrinology in its broadest sense, which is needed at this time of rapid expansion of the field of endocrinology. JPEM publishes Reviews, Original Research, Case Reports, Short Communications and Letters to the Editor (including comments on published papers),. JPEM publishes supplements of proceedings and abstracts of pediatric endocrinology and diabetes society meetings.