Danica Mandić, Aleksandra Milovančev, Aleksandar Redžek, Milovan Petrović, Aleksandra Ilić, Milenko Čanković, Melisa Mironicki Pekarić, Vanja Dudaš, Bojana Šarošković
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引用次数: 0
Abstract
Aim: This study aimed to assess the impact of COVID-19 infection on cardiac surgery outcomes in patients who contracted COVID-19 peri-operatively or had recently recovered from COVID-19.
Methods: The study prospectively enrolled 95 patients scheduled for cardiac surgery who had recently recovered from COVID-19. This formed the post-COVID-19 group. The other group consisted of 25 patients who contracted COVID-19 peri-operatively. Patients were followed for all-cause mortality as the primary endpoint and postoperative course complications as the secondary endpoint. Data were compared to a historical cohort of 280 non-COVID-19 patients.
Results: The peri-operative COVID-19 group exhibited a significantly higher prevalence of primary outcome all-cause mortality (28%), compared with 4.3% in the controls (p < 0.01), as well as the secondary composite endpoint (stroke, peri-operative myocardial infarction and pneumonia) (52 vs 13.9%, p < 0.01). The post-COVID-19 group had a higher incidence of acute pulmonary embolism (3.2 vs 0%, p < 0.01) and atrial fibrillation (23.4 vs 11.4%, p < 0.01).
Conclusion: Patients who contracted COVID-19 peri-operatively had an increased rate of mortality and postoperative complications, while cardiac surgery in the recently recovered COVID-19 group was associated with a higher incidence of pulmonary embolism and atrial fibrillation.
目的:本研究旨在评估COVID-19感染对围术期感染COVID-19或刚从COVID-19感染中康复的患者心脏手术预后的影响:该研究前瞻性地招募了95名计划接受心脏手术且刚从COVID-19感染中康复的患者。这就是COVID-19术后组。另一组包括25名在围手术期感染COVID-19的患者。患者的主要终点是全因死亡率,次要终点是术后并发症。数据与280名非COVID-19患者的历史数据进行了比较:结果:COVID-19围手术期组全因死亡率(28%)明显高于对照组的4.3%(P < 0.01),次要综合终点(中风、围手术期心肌梗死和肺炎)也明显高于对照组(52 vs 13.9%,P < 0.01)。COVID-19术后组的急性肺栓塞(3.2 vs 0%,p < 0.01)和心房颤动(23.4 vs 11.4%,p < 0.01)发生率更高:结论:围手术期感染COVID-19的患者死亡率和术后并发症发生率增加,而COVID-19新近痊愈组的心脏手术与肺栓塞和心房颤动发生率较高有关。
期刊介绍:
The Cardiovascular Journal of Africa (CVJA) is an international peer-reviewed journal that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular disease. Topics covered include coronary disease, electrophysiology, valve disease, imaging techniques, congenital heart disease (fetal, paediatric and adult), heart failure, surgery, and basic science.