Estimation of the incubation time distribution in the singly and doubly interval censored model

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-02-21 DOI:10.1111/stan.12335

Piet Groeneboom

引用次数: 0

Abstract

We analyze nonparametric estimators for the distribution function of the incubation time in the singly and doubly interval censoring model. The classical approach is to use parametric families like Weibull, log‐normal or gamma distributions in the estimation procedure. We propose nonparametric estimates for functions of the observations, which stay closer to the data than the classical parametric methods. We also give explicit limit distributions for discrete versions of the models and apply this to compute confidence intervals. The methods complement the analysis of the continuous model in Groeneboom (2021, 2023). R scripts for computation of the estimates are provided in Groeneboom (2020).

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单区间和双区间普查模型中孵化时间分布的估计

我们分析了单区间和双区间普查模型中孵化时间分布函数的非参数估计器。经典的方法是在估计过程中使用参数族，如 Weibull、log-normal 或 gamma 分布。我们提出了观测值函数的非参数估计，它比传统的参数方法更接近数据。我们还给出了离散模型的明确极限分布，并将其用于计算置信区间。这些方法是对 Groeneboom (2021, 2023) 中连续模型分析的补充。计算估计值的 R 脚本在 Groeneboom (2020) 中提供。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.