Fast-track anesthesia and outcomes in hepatopancreatic cancer surgery: a retrospective analysis.

Sebastiano Mercadante, Fabrizio David, Lucio Mandalà, Patrizia Villari, Pietro Mezzatesta, Alessandra Casuccio
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Abstract

Aim: To assess the feasibility of a fast-track anesthesia protocol for hepatopancreatobiliary cancer surgery.

Methods: Retrospective analysis of consecutive sample of patients who underwent hepatopancreatic surgery for cancer for a period of 12 months in a high volume cancer center. Blended anesthesia was performed for most patients who were then observed in a recovery room area until achieving a safety score.

Results: Data of 163 patients were examined. Fifty-six and 107 patients underwent surgery for pancreatic cancer and liver surgery for primary tumor or metastases, respectively. Most patients were ASA 3. The mean durations of anesthesia and surgery were 322 min (SD 320) and 296 min (SD 133), respectively. Extubation was performed in the operating room in 125 patients. Post-operatory invasive ventilation was maintained in the recovery room in fifteen patients for a mean duration of 72.7 min (SD148.2). Only one patient was admitted to intensive care for 15 h. NIV was performed in three patients for a mean duration of 73.3 min (SD 15.3). The mean recovery room staying was 79 min (SD 80). The mean hospital postoperative stay was a mean of 8.1 days (SD 5.7). No complications were found in 144 patients. Globally, mortality rate was 3%.

Conclusion: A program of fast-track anesthesia with a short stay in recovery room allowed to achieve a good outcome, limiting the costs of intensive care admission.

肝胰腺癌手术中的快速麻醉与疗效:回顾性分析。
目的:评估肝胆胰癌症手术快速麻醉方案的可行性:方法:对一家大型癌症中心 12 个月内接受肝胆胰癌症手术的连续样本患者进行回顾性分析。对大多数患者实施了混合麻醉,然后在恢复室区域对患者进行观察,直至获得安全评分:结果:研究了 163 名患者的数据。56名和107名患者分别接受了胰腺癌手术和肝脏原发肿瘤或转移手术。麻醉和手术的平均持续时间分别为 322 分钟(标准差 320 分钟)和 296 分钟(标准差 133 分钟)。125名患者在手术室拔管。15名患者术后在恢复室进行了有创通气,平均持续时间为72.7分钟(SD148.2)。仅有一名患者在重症监护室住院 15 小时。有三名患者进行了 NIV 治疗,平均持续时间为 73.3 分钟(SD 15.3)。恢复室的平均停留时间为 79 分钟(标准差为 80 分钟)。术后平均住院时间为 8.1 天(标清 5.7 天)。144 名患者均未发现并发症。全球死亡率为 3%:结论:在恢复室短期停留的快速麻醉方案可取得良好的效果,同时限制了重症监护的费用。
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