Long-Term Outcomes in Severe Community-Acquired Pneumonia.

IF 2.3 3区 医学 Q2 CRITICAL CARE MEDICINE
Francesco Carella, Stefano Aliberti, Anna Stainer, Antonio Voza, Francesco Blasi
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引用次数: 0

Abstract

Community-acquired pneumonia (CAP) is globally one of the major causes of hospitalization and mortality. Severe CAP (sCAP) presents great challenges and need a comprehensive understanding of its long-term outcomes. Cardiovascular events and neurological impairment, due to persistent inflammation and hypoxemia, contribute to long-term outcomes in CAP, including mortality. Very few data are available in the specific population of sCAP. Multiple studies have reported variable 1-year mortality rates for patients with CAP up to 40.7%, with a clear influence by age, comorbidities, and disease severity. In terms of treatment, the potential protective role of macrolides in reducing mortality emphasizes the importance of appropriate empiric antibiotic therapy. This narrative review explores the growing interest in the literature focusing on the long-term implications of sCAP. Improved understanding of long-term outcomes in sCAP can facilitate targeted interventions and enhance posthospitalization care protocols.

严重社区获得性肺炎的长期疗效。
社区获得性肺炎(CAP)是全球住院和死亡的主要原因之一。重症 CAP(sCAP)带来了巨大挑战,需要全面了解其长期结果。由于炎症和低氧血症的持续存在,心血管事件和神经功能损伤会导致 CAP 的长期后果,包括死亡率。针对 sCAP 特定人群的数据很少。多项研究报告显示,CAP 患者的 1 年死亡率各不相同,最高可达 40.7%,其中年龄、合并症和疾病严重程度的影响非常明显。在治疗方面,大环内酯类药物在降低死亡率方面的潜在保护作用强调了适当的经验性抗生素治疗的重要性。这篇叙述性综述探讨了越来越多的文献关注 sCAP 的长期影响。加深对 sCAP 长期影响的了解有助于采取有针对性的干预措施,并加强住院后的护理方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.10
自引率
0.00%
发文量
87
审稿时长
6-12 weeks
期刊介绍: The journal focuses on new diagnostic and therapeutic procedures, laboratory studies, genetic breakthroughs, pathology, clinical features and management as related to such areas as asthma and other lung diseases, critical care management, cystic fibrosis, lung and heart transplantation, pulmonary pathogens, and pleural disease as well as many other related disorders.The journal focuses on new diagnostic and therapeutic procedures, laboratory studies, genetic breakthroughs, pathology, clinical features and management as related to such areas as asthma and other lung diseases, critical care management, cystic fibrosis, lung and heart transplantation, pulmonary pathogens, and pleural disease as well as many other related disorders.
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