Relationship and Accuracy of Urine Lead as an Alternative to Blood Lead Biomarker among Panel Beaters in Enugu Metropolis: Nigeria.

IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Indian Journal of Occupational and Environmental Medicine Pub Date : 2023-10-01 Epub Date: 2023-12-30 DOI:10.4103/ijoem.ijoem_140_22

Chukwukasi Wilson Kassy

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Abstract

Background and aims: The limited alternatives to blood lead biomarkers continue to affect the control of occupational lead exposures. This study assessed the relationship and accuracy of urine lead biomarker as an alternative to blood lead biomarker among roadside and organized panel beaters in Enugu metropolis, Nigeria.

Methods: This was a cross-sectional analytical study of 428 panel beaters in Enugu metropolis. Samples collected were analyzed using Atomic Absorption Spectrometer (AAS) at 283.3 nm wavelengths. Data were analyzed using correlation and receiver operating characteristics (ROC).

Result: A linear positive relationship with high accuracy and sensitivity were found between blood and urine biomarkers.

Conclusion: Urine biomarker has a linear relationship with blood biomarker and showed a significant accuracy for the measurement of occupational lead exposure. Therefore, a urinary biomarker can serve as an alternative replacement to blood lead in occupational health practice.

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尿铅作为埃努古市打板者血铅生物标志物替代物的关系和准确性：尼日利亚。

背景和目的：血铅生物标志物的替代品有限，这继续影响着对职业铅暴露的控制。本研究评估了尿铅生物标志物与血铅生物标志物之间的关系和准确性，尿铅生物标志物可替代尼日利亚埃努古市路边和有组织的打板工人的血铅生物标志物：这是一项横断面分析研究，研究对象是埃努古市的 428 名打板者。采集的样本使用波长为 283.3 nm 的原子吸收光谱仪 (AAS) 进行分析。使用相关性和接收器操作特性（ROC）对数据进行了分析：结果：血液和尿液生物标记物之间呈线性正相关，准确性和灵敏度都很高：结论：尿液生物标志物与血液生物标志物呈线性关系，在测量职业性铅暴露方面具有显著的准确性。因此，在职业健康实践中，尿液生物标志物可以替代血铅。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Occupational and Environmental Medicine PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

1.60

自引率

0.00%

发文量

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