Novel hydrazone schiff’s base derivatives of polyhydroquinoline: synthesis, in vitro prolyl oligopeptidase inhibitory activity and their Molecular docking study

Journal of Biomolecular Structure and Dynamics Pub Date : 2024-02-22 DOI:10.1080/07391102.2024.2319677

Faiz Talab, Aftab Alam, Zainab, Saeed Ullah, Ahmed A. Elhenawy, Syed Adnan Ali Shah, Mumtaz Ali, Sobia Ahsan Halim, Ajmal Khan, Abdul Latif, Ahmed Al-Harrasi, Manzoor Ahmad

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Abstract

This research work reports the synthesis of new derivatives of the hydrazone Schiff bases (1–17) based on polyhydroquinoline nucleus through multistep reactions. HR-ESIMS,1H- and 13C-NMR spectrosco...

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多氢喹啉的新型腙裂基衍生物：合成、体外脯氨酰寡肽酶抑制活性及其分子对接研究

本研究报告通过多步反应合成了基于多氢喹啉核的腙席夫碱新衍生物（1-17）。这些衍生物的HR-ESIMS、1H-和13C-NMR谱图均显示了它们的...

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of Biomolecular Structure and Dynamics

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