Understanding Australian Pharmacists' Perceptions on the Utilisation of Oral 5-HT3 Antagonists as Pharmacist-Only Anti-Emetics in Comparison to Oral D2 Antagonists.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-02-21 DOI:10.1177/08971900241236379

Aiden Hendry, Jack Janetzki, Wern Chern Chai

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引用次数: 0

Abstract

Objectives: To investigate the perception of community pharmacists on the down-scheduling of 5-HT3 antagonists to pharmacist-only-medicine for treatment of acute nausea and/or vomiting in Australia. Methods: A nationwide anonymous survey targeting Australian community pharmacists was conducted from April to May 2023. Responses were collected and analysed quantitively or qualitatively, where appropriate. Key findings: Participants reported that 5-HT3 antagonists were effective at treating nausea and/or vomiting and would likely recommend their use. Training is required to manage supply due to concerns related to their side effects. Conclusion: Participants supported down-scheduling of 5-HT3 antagonists for the treatment of nausea and/or vomiting in Australia. A pilot study on the provision of 5-HT3 antagonists by pharmacists is recommended as is the development of guidelines for pharmacist-only supply before down-scheduling is considered.

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了解澳大利亚药剂师对口服 5-HT3 拮抗剂与口服 D2 拮抗剂作为药剂师专用抗化妆品的使用情况的看法。

目的：调查社区药剂师对澳大利亚将 5-HT3 拮抗剂下调为药剂师专用药物治疗急性恶心和/或呕吐的看法：调查澳大利亚社区药剂师对将治疗急性恶心和/或呕吐的 5-HT3 拮抗剂下调为药剂师专用药物的看法。调查方法2023 年 4 月至 5 月，针对澳大利亚社区药剂师开展了一项全国性匿名调查。调查收集了答复，并酌情进行了定量或定性分析。主要研究结果：参与者称 5-HT3 拮抗剂可有效治疗恶心和/或呕吐，并可能会推荐使用。由于担心5-HT3拮抗剂的副作用，因此需要对供应管理进行培训。结论：在澳大利亚，与会者支持减少用于治疗恶心和/或呕吐的 5-HT3 拮抗剂的用量。建议对药剂师提供 5-HT3 拮抗剂的情况进行试点研究，并在考虑下调计划之前制定药剂师独家供应指南。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.