Evaluation of quality of life in children with precocious puberty

IF 3 3区医学 Q2 ENDOCRINOLOGY & METABOLISM

Clinical Endocrinology Pub Date : 2024-02-20 DOI:10.1111/cen.15033

İlkay N. Yılmazer, Sema Nilay Abseyi, Gizem Şenyazar, Merih Berberoğlu, Zeynep Şıklar, Zehra Aycan

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Abstract

Objective

This study aimed to investigate the quality of life of patients with central precocious puberty (CPP) who required treatment and premature thelarche (PT) followed up without treatment and to compare the groups with and without treatment among themselves and with healthy children.

Design, Patients and Measurement

This study is designed as a case–control study. A total of 193 children including 59 children with CPP, 53 children with PT, 81 healthy children and their parents were included in the study. A questionnaire was applied to evaluate the sociodemographic characteristics that would affect the quality of life. The ‘Pediatric Quality of Life Inventory (PedsQL)’ was used to assess the quality of life.

Results

The PedsQL total scale score was 78.10 ± 17.13, 79.35 ± 11.54 and 79.52 ± 14.65, the psychosocial health summary score was 78.86 ± 16.83, 79.40 ± 12.54 and 79.94 ± 14.94 and physical health summary score was 75.81 ± 20.69, 79.41 ± 15.04 and 78.25 ± 17.52 in CPP, PT and control groups, respectively; however, there was no statistical difference (p > .05). In the scale administered to the parents, scores were similar in the three groups. No difference was found between CPP, PT and control groups in terms of sociodemographic data in the study (p > .05).

Conclusion

Unlike previous studies, in this study the effects of sociodemographic characteristics and whether treatment was initiated or not on quality of life were investigated. Although the scale scores of the CPP group were lower than the PT and control group, there was no statistically significant difference, indicating that quality of life was not negatively affected in the CPP group receiving treatment.

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评估性早熟儿童的生活质量。

研究目的本研究旨在调查需要治疗的中枢性性早熟（CPP）患者和未接受治疗的过早性早熟（PT）患者的生活质量，并比较接受治疗组和未接受治疗组之间以及与健康儿童之间的生活质量：本研究为病例对照研究。共有 193 名儿童参与了研究，其中包括 59 名 CPP 患儿、53 名 PT 患儿、81 名健康儿童及其家长。研究采用问卷调查的方式，对影响生活质量的社会人口学特征进行评估。儿科生活质量量表（PedsQL）"用于评估生活质量：结果：CPP组、PT组和对照组的儿科生活质量量表总分分别为（78.10 ± 17.13）、（79.35 ± 11.54）和（79.52 ± 14.65）分，社会心理健康总分分别为（78.86 ± 16.83）、（79.40 ± 12.54）和（79.94 ± 14.94）分，身体健康总分分别为（75.81 ± 20.69）、（79.41 ± 15.04）和（78.25 ± 17.52）分，但无统计学差异（P > .05）。在给家长的量表中，三组的得分相似。在社会人口学数据方面，CPP 组、PT 组和对照组之间没有差异（P > .05）：与以往的研究不同，本研究调查了社会人口学特征和是否开始治疗对生活质量的影响。虽然 CPP 组的量表评分低于 PT 组和对照组，但在统计学上没有显著差异，这表明接受治疗的 CPP 组的生活质量没有受到负面影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Endocrinology 医学-内分泌学与代谢

CiteScore

6.40

自引率

3.10%

发文量

192

审稿时长

1 months

期刊介绍： Clinical Endocrinology publishes papers and reviews which focus on the clinical aspects of endocrinology, including the clinical application of molecular endocrinology. It does not publish papers relating directly to diabetes care and clinical management. It features reviews, original papers, commentaries, correspondence and Clinical Questions. Clinical Endocrinology is essential reading not only for those engaged in endocrinological research but also for those involved primarily in clinical practice.