A Longitudinal Examination of Obsessive-Compulsive Symptom Severity as a Predictor of Posttraumatic Stress Disorder Development

Mia Mantei
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Abstract

It is well established in literature that Obsessive Compulsive Disorder (OCD) and Posttraumatic Stress Disorder (PTSD) have high rates of comorbidity. Many studies consider trauma exposure as an etiological factor in the development of Obsessive Compulsive (OC) symptoms, however no research to date has considered the contributions of OC symptoms in the development and maintenance of posttraumatic stress symptoms (PTSS) following a traumatic event. Previous literature reports that trauma type and distress tolerance both influence presence and severity of PTSS and OC symptoms. The present study utilizes archival data from 97 trauma-exposed participants selected from a larger randomized controlled trial of four web-based interventions for anxiety and mood symptoms (N = 303). A hierarchical linear regression indicated that baseline OC symptoms predicted long-term follow-up PTSS over and above the variance explained by baseline PTSS, treatment condition, and trauma load. Further, a significant trauma type by OC symptom severity interaction indicated that baseline OC symptom severity had a greater effect on the development or maintenance of PTSS for individuals who experienced interpersonal trauma, as compared to those who experienced non-interpersonal trauma. Additionally, a mediation model demonstrated that month 3 distress tolerance fully mediated the relationship between baseline OC symptoms and long-term follow-up PTSS. The present study was limited by possible treatment effects, outdated methodologies utilized in the original study, and attrition. Despite its limitations the current study provides novel findings and advances our understanding of the relationship between OCD and PTSD symptoms.
将强迫症状严重程度作为创伤后应激障碍发展预测因素的纵向研究
有文献证实,强迫症(OCD)和创伤后应激障碍(PTSD)的合并率很高。许多研究认为,创伤暴露是强迫症(OC)症状形成的病因之一,但迄今为止,还没有研究考虑过强迫症症状在创伤事件后创伤后应激障碍(PTSS)的形成和维持中的作用。以前的文献报道,创伤类型和痛苦耐受性都会影响 PTSS 和 OC 症状的存在和严重程度。本研究利用了从一项针对焦虑和情绪症状的四种网络干预措施(N = 303)的大型随机对照试验中挑选出的 97 名受创伤参与者的档案数据。分层线性回归结果表明,基线 OC 症状对长期随访 PTSS 的预测超过了基线 PTSS、治疗条件和创伤负荷所能解释的方差。此外,创伤类型与 OC 症状严重程度之间存在明显的交互作用,这表明与经历过非人际创伤的人相比,经历过人际创伤的人的基线 OC 症状严重程度对 PTSS 的发展或维持有更大的影响。此外,一个中介模型表明,第 3 个月的痛苦耐受性完全中介了基线 OC 症状与长期随访的 PTSS 之间的关系。本研究受到了可能的治疗效果、原始研究中使用的过时方法以及自然减员的限制。尽管存在局限性,但本研究提供了新的发现,并加深了我们对强迫症和创伤后应激障碍症状之间关系的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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