Collagen: A periodontium saviour

Q3 Biochemistry, Genetics and Molecular Biology
Shivani Sachdeva, Amit Mani, Shweta Vikhe, Anjali Pandit, Pranjali Jagtap
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引用次数: 0

Abstract

Collagen is a fibrillar protein that conforms the conjunctive and connective tissues in the human body, essentially skin, joints, and bones. It is one of the most abundant molecule in many of the living organisms due to its connective role in biological structure. It is a highly versatile material, extensively used in the medical, dental, and pharmacological fields. Collagen is capable of being prepared into cross-linked compacted solids or into lattice-like gels. The collagen family consists of at least 30 different genes, which produce 19 known types of collagen. All collagens contain greater or lesser stretches of triple helix. Some of the superior properties of collagen-based biomaterials, such as biocompatibility, biodegradability, mechanical properties, and cell activities, are pinpointed. These properties make collagen applicable in biomedicine, such as wound healing, tissue engineering, surface coating of medical devices, and skin supplementation. The purpose of this article is to review the available literature on collagen with special emphasis on its role in development and maintenance of oral tissues. Also it reviews the types of collagen, it’s structure, sources, role in maintaining periodontal tissues and uses in dentistry.
胶原蛋白:牙周的救星
胶原蛋白是一种纤维状蛋白质,主要用于粘合人体的结缔组织,如皮肤、关节和骨骼。由于胶原蛋白在生物结构中的连接作用,它是许多生物体内含量最高的分子之一。它是一种用途广泛的材料,被广泛应用于医学、牙科和药学领域。胶原蛋白可以制备成交联紧密的固体,也可以制备成网格状凝胶。胶原蛋白家族由至少 30 种不同的基因组成,可产生 19 种已知类型的胶原蛋白。所有胶原蛋白都含有或多或少的三重螺旋。以胶原蛋白为基础的生物材料具有一些优越性能,如生物相容性、生物可降解性、机械性能和细胞活性。这些特性使胶原蛋白适用于生物医学,如伤口愈合、组织工程、医疗器械表面涂层和皮肤补充。本文旨在回顾有关胶原蛋白的现有文献,特别强调胶原蛋白在口腔组织发育和维护中的作用。文章还回顾了胶原蛋白的类型、结构、来源、在维护牙周组织中的作用以及在牙科中的用途。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Cellular Biotechnology
Journal of Cellular Biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
0.70
自引率
0.00%
发文量
13
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