The Peculiarities of Studies on the Stability of Ambronat

Abstract

In this article, the quality indicators for determining the persistence of a cough–stimulating and secretomotor type of drug commonly used in the treatment of inflammatory diseases of the upper respiratory tract were investigated. “Ambronate” qiyami did not change its color, taste and smell during the years of its stability in terms of its appearance. The indicator of рN environment is normally in the range of 5.0–7.5 and during the study it was in the range of 6.3–7.8. The results for the 3 years of the study were presented. In the 2.5–3rd year of storage, the amount of fungi and bacteria in the kiyama increased, and the results of the study in 2.5 years of storage were presented. In the quantitative analysis, the amount of ambroxol hydrochloride was determined by the spectrophotometric method, the obtained results were reflected in the regulatory documents.