A Comprehensive Analysis of Risk Assessment of Particulate Matter in Five Health Centers in Akure, Nigeria

F. Abulude, S. Oluwagbayide, A. Akinnusotu, K. M. Arifalo, Ademola Adamu, A. M. Kenni
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Abstract

This study presents a comprehensive assessment of indoor particulate matter (PM) concentrations, focusing on PM1, PM2.5, and PM10 in five primary health centers (PHCs): Arakale (Urban), the Federal College of Agriculture (FECA) (Urban), Iju (semi-urban), Oba-Ile (semi-urban), and Owode (Rural) within Akure local government areas in Nigeria. The primary novelty of this research lies in its detailed exploration of the toxicity potential of these PM fractions, providing valuable insights into the local air quality and associated health risks. This study assesses the health implications by calculating the toxicity potential (TP), relative risk (RR), excess risk (ER), and attributable fractions (Afs) for cardiopulmonary and lung cancer mortality. The results reveal varying RR values for all-cause mortality, with Arakale showing a slight elevation (RR: 1.061), indicating potential health risks. ER values for cardiopulmonary mortality range from 14.728 ± 7.25 to 19.04 ± 0.38, emphasizing the substantial excess risk associated with long-term PM2.5 exposure. The study also uncovers Afs for cardiopulmonary mortality ranging between 11.03 ± 0.31 and 19.22 ± 0.04, underscoring the significant contribution of PM to cardiovascular and respiratory health risks. Similarly, Afs for lung cancer mortality range from 10.03 ± 0.012 to 17.13 ± 0.10, highlighting the substantial association between PM2.5 exposure and lung cancer risk. These findings underscore the urgent need for targeted air quality management strategies and public health interventions in the studied locations to mitigate the heightened health risks associated with particulate matter pollution. The calculated RR, ER, and AF values offer crucial insights into the complex relationship between PM exposure and adverse health outcomes, providing a foundation for informed decision-making and future research endeavors.
尼日利亚阿库雷市五家医疗中心颗粒物风险评估综合分析
本研究全面评估了五个初级保健中心(PHC)的室内颗粒物(PM)浓度,重点是 PM1、PM2.5 和 PM10:Arakale(城市)、联邦农业学院(FECA)(城市)、Iju(半城市)、Oba-Ile(半城市)和 Owode(农村)。这项研究的主要创新之处在于详细探讨了这些可吸入颗粒物馏分的潜在毒性,为了解当地空气质量和相关健康风险提供了宝贵的见解。本研究通过计算心肺癌和肺癌死亡率的毒性潜力(TP)、相对风险(RR)、超额风险(ER)和可归因分数(Afs)来评估对健康的影响。结果显示,全因死亡率的 RR 值各不相同,阿拉卡莱的 RR 值略有上升(RR:1.061),表明存在潜在的健康风险。心肺死亡率的 ER 值从 14.728 ± 7.25 到 19.04 ± 0.38 不等,强调了与长期暴露于 PM2.5 相关的巨大超额风险。研究还发现,心肺死亡率的 Afs 值介于 11.03 ± 0.31 和 19.22 ± 0.04 之间,强调了 PM 对心血管和呼吸系统健康风险的重大影响。同样,肺癌死亡率的Afs从10.03 ± 0.012到17.13 ± 0.10不等,突显了PM2.5暴露与肺癌风险之间的重大关联。这些研究结果突出表明,迫切需要在研究地点采取有针对性的空气质量管理策略和公共卫生干预措施,以降低与颗粒物污染相关的更高健康风险。计算得出的RR、ER和AF值为了解PM暴露与不良健康后果之间的复杂关系提供了重要依据,为知情决策和未来的研究工作奠定了基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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