{"title":"Occurrence of Arterial Hypertension in Patients with sleep Apnoea Syndrome","authors":"M. Mucska, A. Vyskoc, K. Dostalova, S. Moricova","doi":"10.22359/cswhi_15_1_07","DOIUrl":null,"url":null,"abstract":"Introduction: Sleep apnoea syndrome (SAS) is a serious under-diagnosed chronic disease, which often coincides with arterial hypertension (AH). The U.S. Joint National Committee considers SAS to be the most common cause of secondary arterial hypertension. Objective: To determine the incidence of arterial hypertension in patients diagnosed with SAS in an accredited sleep laboratory (ASL) in Bratislava in the years 2013-2022. Methods: The monitored group consisted of 688 patients examined in an ASL in Bratislava who underwent an initial examination (anamnesis, anthropometry, sleep questionnaire) and a diagnosis of sleep-disordered breathing (nocturnal polysomnography) in order to confirm or refute the diagnosis of OSAS. Data collection also took place by using a copy of the patients’ medical records (presence of AH). We used Microsoft Excel and statistical software SPSS, version 21.0 to process the obtained data. We considered the result to be statistically significant if p ≤ 0.05. Results: We demonstrated a statistically significant difference in the incidence of AH in patients with SAS compared to patients without SAS, i.e., there was a statistically significantly higher incidence of AH in patients with SAS compared to patients without SAS (39% vs. 17.5%; OR=3.0; p<0.001). We also demonstrated that the higher the AHI value in patients with SAS, the higher the incidence of AH (p=0.002; 95% CI 1.4 – 4.4). In addition, there was a 1.9 times higher risk of developing AH in patients with a moderate degree of SAS compared to patients with a mild degree of SAS (p=0.014) and up to a 2.8 times higher risk of developing AH in patients with a severe degree of SAS compared to patients with moderate SAS (p<0.001) regardless of BMI. Conclusion: Due to the high coincidence (1/3) of arterial hypertension and sleep apnoea syndrome in the monitored group, it is necessary to focus on effective screening of SAS in high-risk persons as well as effective screening of SAS in persons with present AH.","PeriodicalId":42256,"journal":{"name":"Clinical Social Work and Health Intervention","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Social Work and Health Intervention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22359/cswhi_15_1_07","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Sleep apnoea syndrome (SAS) is a serious under-diagnosed chronic disease, which often coincides with arterial hypertension (AH). The U.S. Joint National Committee considers SAS to be the most common cause of secondary arterial hypertension. Objective: To determine the incidence of arterial hypertension in patients diagnosed with SAS in an accredited sleep laboratory (ASL) in Bratislava in the years 2013-2022. Methods: The monitored group consisted of 688 patients examined in an ASL in Bratislava who underwent an initial examination (anamnesis, anthropometry, sleep questionnaire) and a diagnosis of sleep-disordered breathing (nocturnal polysomnography) in order to confirm or refute the diagnosis of OSAS. Data collection also took place by using a copy of the patients’ medical records (presence of AH). We used Microsoft Excel and statistical software SPSS, version 21.0 to process the obtained data. We considered the result to be statistically significant if p ≤ 0.05. Results: We demonstrated a statistically significant difference in the incidence of AH in patients with SAS compared to patients without SAS, i.e., there was a statistically significantly higher incidence of AH in patients with SAS compared to patients without SAS (39% vs. 17.5%; OR=3.0; p<0.001). We also demonstrated that the higher the AHI value in patients with SAS, the higher the incidence of AH (p=0.002; 95% CI 1.4 – 4.4). In addition, there was a 1.9 times higher risk of developing AH in patients with a moderate degree of SAS compared to patients with a mild degree of SAS (p=0.014) and up to a 2.8 times higher risk of developing AH in patients with a severe degree of SAS compared to patients with moderate SAS (p<0.001) regardless of BMI. Conclusion: Due to the high coincidence (1/3) of arterial hypertension and sleep apnoea syndrome in the monitored group, it is necessary to focus on effective screening of SAS in high-risk persons as well as effective screening of SAS in persons with present AH.
简介睡眠呼吸暂停综合征(SAS)是一种严重诊断不足的慢性疾病,通常与动脉高血压(AH)同时存在。美国国家联合委员会认为,睡眠呼吸暂停综合征是继发性动脉高血压最常见的病因。目的:确定动脉高血压的发病率:确定 2013-2022 年在布拉迪斯拉发一家经认可的睡眠实验室(ASL)中被诊断为 SAS 患者的动脉高血压发病率。研究方法监测组包括在布拉迪斯拉发一家认可睡眠实验室接受检查的 688 名患者,他们都接受了初步检查(病史、人体测量、睡眠问卷)和睡眠呼吸障碍诊断(夜间多导睡眠图),以确诊或反驳 OSAS 诊断。数据收集还使用了患者的病历副本(有无 AH)。我们使用 Microsoft Excel 和 21.0 版 SPSS 统计软件处理所获得的数据。如果 p≤ 0.05,我们认为结果具有统计学意义。结果我们发现,与无 SAS 患者相比,有 SAS 患者的 AH 发生率有明显的统计学差异,即有 SAS 患者的 AH 发生率明显高于无 SAS 患者(39% vs. 17.5%;OR=3.0;P<0.001)。我们还发现,SAS 患者的 AHI 值越高,AH 的发生率也越高(p=0.002;95% CI 1.4 - 4.4)。此外,与轻度 SAS 患者相比,中度 SAS 患者发生 AH 的风险高出 1.9 倍(p=0.014),与中度 SAS 患者相比,重度 SAS 患者发生 AH 的风险高出 2.8 倍(p<0.001),与体重指数无关。结论由于监测组中动脉高血压和睡眠呼吸暂停综合征的发生率很高(1/3),因此有必要重点对高危人群进行有效的 SAS 筛查,并对存在 AH 的人群进行有效的 SAS 筛查。