Inequalities in oral health: Estimating the longitudinal economic burden of dental caries by deprivation status in six countries

Gerard Dunleavy, Neeladri Verma, Radha Raghupathy, Shivangi Jain, Joao Hofmeister, Rob Cook, Marko Vujicic, Moritz Kebschull, Iain Chapple, Nicola West, Nigel Pitts
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Abstract

Background The recent World Health Organization (WHO) resolution on oral health urges pivoting to a preventive approach and integration of oral health into the non-communicable diseases agenda. This study aimed to: 1) explore the healthcare costs of managing dental caries between the ages of 12 and 65 years across socioeconomic groups in six countries (Brazil, France, Germany, Indonesia, Italy, UK), and 2) estimate the potential reduction in direct costs from non-targeted and targeted oral health-promoting interventions. Methods A cohort simulation model was developed to estimate direct costs of over time for different socioeconomic groups. National-level DMFT (dentine threshold) data, the relative likelihood of receiving an intervention (such as a restorative procedure, tooth extraction and replacement), and clinically-guided assumptions were used to populate the model. A hypothetical group of upstream and downstream preventive interventions were applied either uniformly across all deprivation groups to reduce caries progression rates by 30% or in a levelled-up fashion with the greatest gains seen in the most deprived group. Results The population level direct costs of caries from 12 to 65 years of age varied between US10.2bn in Italy to US$36.2bn in Brazil. The highest per-person costs were in the UK at US$22,910 and the lowest in Indonesia at US$7,414. The per-person direct costs were highest in the most deprived group across Brazil, France, Italy and the UK. With the uniform application of preventive measures across all deprivation groups, the greatest reduction in per-person costs for caries management was seen in the most deprived group across all countries except Indonesia. With a levelling-up approach, cost reductions in the most deprived group ranged from US$3,948 in Indonesia to US$17,728 in the UK. Conclusion Our exploratory analysis shows the disproportionate economic burden of caries in the most deprived groups and highlights the significant opportunity to reduce direct costs via levelling-up preventive measures. The healthcare burden stems from a higher baseline caries experience and greater annual progression rates in the most deprived. Therefore, preventive measures should be primarily aimed at reducing early childhood caries, but also applied across all ages.
口腔健康的不平等:按六个国家的贫困状况估算龋齿的纵向经济负担
背景世界卫生组织(WHO)最近关于口腔健康的决议敦促转向预防方法,并将口腔健康纳入非传染性疾病议程。本研究旨在1)探讨六个国家(巴西、法国、德国、印度尼西亚、意大利、英国)不同社会经济群体在 12 岁至 65 岁之间管理龋齿的医疗成本;以及 2)估算非目标性和目标性口腔健康促进干预措施可能减少的直接成本。方法 建立队列模拟模型,估算不同社会经济群体在不同时期的直接成本。模型中使用了国家级 DMFT(牙本质阈值)数据、接受干预(如修复手术、拔牙和换牙)的相对可能性以及临床指导假设。一组假定的上游和下游预防性干预措施被统一应用于所有贫困群体,以降低 30% 的龋病进展率,或者以分级方式应用于最贫困群体,以获得最大收益。结果 12 至 65 岁人群的龋病直接成本从意大利的 102 亿美元到巴西的 362 亿美元不等。巴西、法国、意大利和英国最贫困群体的人均直接成本最高。在所有贫困群体中统一采用预防措施后,除印度尼西亚外,所有国家中最贫困群体的人均龋齿管理成本降幅最大。如果采用平均化方法,最贫困群体的成本降幅从印度尼西亚的 3,948 美元到英国的 17,728 美元不等。结论我们的探索性分析表明,龋病给最贫困群体造成的经济负担过重,并强调了通过提高预防措施的水平来降低直接成本的重大机遇。医疗负担源于最贫困人群较高的龋齿基线经验和较高的年进展率。因此,预防措施应以减少幼儿龋齿为主要目标,但也应适用于所有年龄段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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