Use of Registries and Large Databases for Toxicology Research.

IF 2.5 4区 医学 Q3 TOXICOLOGY
Journal of Medical Toxicology Pub Date : 2024-09-01 Epub Date: 2024-02-16 DOI:10.1007/s13181-024-00997-z
Maryann Mazer-Amirshahi, Daniel A Laub, Mark B Mycyk
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引用次数: 0

Abstract

The advancement of medical toxicology knowledge has traditionally relied on case reports and case series because of the ethical challenges involved in studying poisoned patients. The growing availability of several large databases and registries now allows researchers to describe and analyze patterns in poisoned patients who share a particular exposure, outcome, or condition. A large database or registry can be useful in generating hypotheses, supporting extramural funding applications, and planning more rigorous studies. Knowing how to access and interpret data in registries such as NPDS, NHAMCS, and HCUP is essential for all stakeholders engaged in medical toxicology research. This review describes the strengths and limitations of different toxicology-relevant registries and databases and how to leverage these powerful tools to advance the science in the field of medical toxicology.

将登记册和大型数据库用于毒理学研究。
医学毒理学知识的发展历来依赖于病例报告和系列病例,因为研究中毒患者涉及伦理挑战。现在,越来越多的大型数据库和登记处允许研究人员描述和分析具有特定暴露、结果或状况的中毒患者的模式。大型数据库或登记处有助于提出假设、支持校外资助申请以及规划更严格的研究。了解如何访问和解释 NPDS、NHAMCS 和 HCUP 等登记册中的数据,对于从事医学毒理学研究的所有相关人员来说都至关重要。本综述介绍了不同毒理学相关登记处和数据库的优势和局限性,以及如何利用这些强大的工具来推动医学毒理学领域的科学发展。
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来源期刊
CiteScore
5.40
自引率
10.30%
发文量
46
期刊介绍: Journal of Medical Toxicology (JMT) is a peer-reviewed medical journal dedicated to advances in clinical toxicology, focusing on the diagnosis, management, and prevention of poisoning and other adverse health effects resulting from medications, chemicals, occupational and environmental substances, and biological hazards. As the official journal of the American College of Medical Toxicology (ACMT), JMT is managed by an editorial board of clinicians as well as scientists and thus publishes research that is relevant to medical toxicologists, emergency physicians, critical care specialists, pediatricians, pre-hospital providers, occupational physicians, substance abuse experts, veterinary toxicologists, and policy makers.       JMT articles generate considerable interest in the lay media, with 2016 JMT articles cited by various social media sites, the Boston Globe, and the Washington Post among others.     For questions or comments about the journal, please contact jmtinfo@acmt.net.    For questions or comments about the journal, please contact jmtinfo@acmt.net.
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